Use of polymer supported reagents for clean multi-step organic synthesis:: preparation of amines and amine derivatives from alcohols for use in compound library generation

被引：62
作者：
Ley, SV
Bolli, MH
Hinzen, B
Gervois, AG
Hall, BJ
机构：
[1] Univ Cambridge, Dept Chem, Cambridge CB2 1EW, England
[2] Cambridge Combinatorial Ltd, Merrifield Ctr, Cambridge CB1 3LQ, England
来源：
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1998年 / 15期
关键词：
D O I：
10.1039/a803611j
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The automated sequential application of polymer supported perruthenate (PSP) and polymer supported cyanoborohydride (PSCBH) in an oxidation-reductive amination procedure allowed the efficient transformation of simple alcohols into more complex amines which can be further derivatised by the use of polymer bound amino sulfonylpyridinium chlorides.
引用
收藏
页码：2239 / 2241
页数：3
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