Estrogen Receptors and Melanoma: A Review

被引：50

作者：

Dika, Emi ^{[1
]}

Patrizi, Annalisa ^{[1
]}

Lambertini, Martina ^{[1
]}

Manuelpillai, Nicholas ^{[1
]}

Fiorentino, Michelangelo ^{[2
]}

Altimari, Annalisa ^{[3
]}

Ferracin, Manuela ^{[2
]}

Lauriola, Mattia ^{[4
]}

Fabbri, Enrica ^{[2
]}

Campione, Elena ^{[5
]}

Veronesi, Giulia ^{[1
]}

Scarfi, Federica ^{[1
]}

机构：

[1] Univ Bologna, DIMES, Dept Expt Diagnost & Specialty Med, Dermatol Sect, I-40138 Bologna, Italy

[2] Univ Bologna, DIMES, Dept Expt Diagnost & Specialty Med, Pathol Unit, I-40138 Bologna, Italy

[3] SOrsola Malpighi Hosp, Lab Oncol Mol Pathol, I-40138 Bologna, Italy

[4] Univ Bologna, DIMES, Dept Expt Diagnost & Specialty Med, Histol Embryol & Appl Biol Unit, I-40138 Bologna, Italy

[5] Univ Roma Tor Vergata, Dept Syst Med, Div Dermatol, I-00133 Rome, Italy

来源：

CELLS | 2019年 / 8卷 / 11期

关键词：

melanoma; woman; estrogens; CUTANEOUS MALIGNANT-MELANOMA; ORAL-CONTRACEPTIVE USE; BREAST-CANCER; REPRODUCTIVE FACTORS; SEX-DIFFERENCES; POOLED ANALYSIS; EUROPEAN ORGANIZATION; HORMONAL FACTORS; GENE-EXPRESSION; MESSENGER-RNA;

D O I：

10.3390/cells8111463

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

In the last three decades cutaneous melanoma has been widely investigated as a steroid hormone-sensitive cancer. Following this hypothesis, many epidemiological studies have investigated the relationship between estrogens and melanoma. No evidence to date has supported this association due to the great complexity of genetic, external and environmental factors underlying the development of this cancer. Molecular mechanisms through which estrogen and their receptor exert a role in melanoma genesis are still under investigation with new studies increasingly focusing on the discovery of new molecular targets for therapeutic treatments.

引用

页数：13

共 107 条

[1] Cancer-specific variation in emergency presentation by sex, age and deprivation across 27 common and rarer cancers
Abel, G. A.
Shelton, J.
Johnson, S.
Elliss-Brookes, L.
Lyratzopoulos, G.
[J]. BRITISH JOURNAL OF CANCER, 2015, 112 : S129 - S136
[2] A CASE-CONTROL STUDY OF THE POSSIBLE ASSOCIATION BETWEEN ORAL-CONTRACEPTIVES AND MALIGNANT-MELANOMA
ADAM, SA
SHEAVES, JK
WRIGHT, NH
MOSSER, G
HARRIS, RW
VESSEY, MP
[J]. BRITISH JOURNAL OF CANCER, 1981, 44 (01) : 45 - 50
[3] The micro-ribonucleic acid (miRNA) miR-206 targets the human estrogen receptor-α (ERα) and represses ERα messenger RNA and protein expression in breast cancer cell lines
Adams, Brian D.
Furneaux, Henry
White, Bruce A.
[J]. MOLECULAR ENDOCRINOLOGY, 2007, 21 (05) : 1132 - 1147
[4] Estrogen Receptor β1 Expression Is Regulated by miR-92 in Breast Cancer
Al-Nakhle, Hakeemah
Burns, Philip A.
Cummings, Michele
Hanby, Andrew M.
Hughes, Thomas A.
Satheesha, Sampoorna
Shaaban, Abeer M.
Smith, Laura
Speirs, Valerie
[J]. CANCER RESEARCH, 2010, 70 (11) : 4778 - 4784
[5] Melanoma, thyroid, cervical, and colon cancer risk after use of fertility drugs
Althuis, MD
Scoccia, B
Lamb, EJ
Moghissi, KS
Westhoff, CL
Mabie, JE
Brinton, LA
[J]. AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 2005, 193 (03) : 668 - 674
[6] BAIN C, 1982, JNCI-J NATL CANCER I, V68, P537
[7] Estrogen Receptor Mutations and Changes in Downstream Gene Expression and Signaling
Barone, Ines
Brusco, Lauren
Fuqua, Suzanne A. W.
[J]. CLINICAL CANCER RESEARCH, 2010, 16 (10) : 2702 - 2708
[8] ORAL-CONTRACEPTIVE USE AND MALIGNANT-MELANOMA IN AUSTRALIA
BERAL, V
EVANS, S
SHAW, H
MILTON, G
[J]. BRITISH JOURNAL OF CANCER, 1984, 50 (05) : 681 - 685
[9] MALIGNANT-MELANOMA AND ORAL-CONTRACEPTIVE USE AMONG WOMEN IN CALIFORNIA
BERAL, V
RAMCHARAN, S
FARIS, R
[J]. BRITISH JOURNAL OF CANCER, 1977, 36 (06) : 804 - 809
[10] Pigmentation and Pregnancy Knowing What Is Normal
Bieber, Amy Kalowitz
Martires, Kathryn J.
Stein, Jennifer A.
Grant-Kels, Jane M.
Driscoll, Marcia S.
Pomeranz, Miriam Keltz
[J]. OBSTETRICS AND GYNECOLOGY, 2017, 129 (01) : 168 - 173

← 1 2 3 4 5 6 7 8 9 10 →