EXPLAINABLE AI FOR COVID-19 CT CLASSIFIERS: AN INITIAL COMPARISON STUDY

被引:66
作者
Ye, Qinghao [1 ,2 ]
Xia, Jun [3 ]
Yang, Guang [4 ,5 ]
机构
[1] Univ Calif San Diego, La Jolla, CA 92093 USA
[2] Hangzhou Oceans Smart Boya Co Ltd, Hangzhou, Zhejiang, Peoples R China
[3] Shenzhen Second Peoples Hosp, Radiol Dept, Shenzhen, Peoples R China
[4] Royal Brompton Hosp, London, England
[5] Imperial Coll London, Natl Heart & Lung Inst, London, England
来源
2021 IEEE 34TH INTERNATIONAL SYMPOSIUM ON COMPUTER-BASED MEDICAL SYSTEMS (CBMS) | 2021年
关键词
COVID-19; Explainable AI; Deep Learning; Classification; CT;
D O I
10.1109/CBMS52027.2021.00103
中图分类号
TP39 [计算机的应用];
学科分类号
081203 ; 0835 ;
摘要
Artificial Intelligence (AI) has made leapfrogs in development across all the industrial sectors especially when deep learning has been introduced. Deep learning helps to learn the behaviour of an entity through methods of recognising and interpreting patterns. Despite its limitless potential, the mystery is how deep learning algorithms make a decision in the first place. Explainable AI (XAI) is the key to unlocking AI and the black-box for deep learning. XAI is an AI model that is programmed to explain its goals, logic, and decision making so that the end users can understand. The end users can be domain experts, regulatory agencies, managers and executive board members, data scientists, users that use AI, with or without awareness, or someone who is affected by the decisions of an AI model. Chest CT has emerged as a valuable tool for the clinical diagnostic and treatment management of the lung diseases associated with COVID-19. AI can support rapid evaluation of CT scans to differentiate COVID-19 findings from other lung diseases. However, how these AI tools or deep learning algorithms reach such a decision and which are the most influential features derived from these neural networks with typically deep layers are not clear. The aim of this study is to propose and develop XAI strategies for COVID-19 classification models with an investigation of comparison. The results demonstrate promising quantification and qualitative visualisations that can further enhance the clinician's understanding and decision making with more granular information from the results given by the learned XAI models.
引用
收藏
页码:521 / 526
页数:6
相关论文
共 15 条
  • [1] [Anonymous], Eur Radiol, DOI 10
  • [2] Explainable Artificial Intelligence (XAI): Concepts, taxonomies, opportunities and challenges toward responsible AI
    Barredo Arrieta, Alejandro
    Diaz-Rodriguez, Natalia
    Del Ser, Javier
    Bennetot, Adrien
    Tabik, Siham
    Barbado, Alberto
    Garcia, Salvador
    Gil-Lopez, Sergio
    Molina, Daniel
    Benjamins, Richard
    Chatila, Raja
    Herrera, Francisco
    [J]. INFORMATION FUSION, 2020, 58 : 82 - 115
  • [3] Artificial intelligence for the detection of COVID-19 pneumonia on chest CT using multinational datasets
    Harmon, Stephanie A.
    Sanford, Thomas H.
    Xu, Sheng
    Turkbey, Evrim B.
    Roth, Holger
    Xu, Ziyue
    Yang, Dong
    Myronenko, Andriy
    Anderson, Victoria
    Amalou, Amel
    Blain, Maxime
    Kassin, Michael
    Long, Dilara
    Varble, Nicole
    Walker, Stephanie M.
    Bagci, Ulas
    Ierardi, Anna Maria
    Stellato, Elvira
    Plensich, Guido Giovanni
    Franceschelli, Giuseppe
    Girlando, Cristiano
    Irmici, Giovanni
    Labella, Dominic
    Hammoud, Dima
    Malayeri, Ashkan
    Jones, Elizabeth
    Summers, Ronald M.
    Choyke, Peter L.
    Xu, Daguang
    Flores, Mona
    Tamura, Kaku
    Obinata, Hirofumi
    Mori, Hitoshi
    Patella, Francesca
    Cariati, Maurizio
    Carrafiello, Gianpaolo
    An, Peng
    Wood, Bradford J.
    Turkbey, Baris
    [J]. NATURE COMMUNICATIONS, 2020, 11 (01)
  • [4] Deep Residual Learning for Image Recognition
    He, Kaiming
    Zhang, Xiangyu
    Ren, Shaoqing
    Sun, Jian
    [J]. 2016 IEEE CONFERENCE ON COMPUTER VISION AND PATTERN RECOGNITION (CVPR), 2016, : 770 - 778
  • [5] Weakly Supervised Deep Learning for COVID-19 Infection Detection and Classification From CT Images
    Hu, Shaoping
    Gao, Yuan
    Niu, Zhangming
    Jiang, Yinghui
    Li, Lao
    Xiao, Xianglu
    Wang, Minhao
    Fang, Evandro Fei
    Menpes-Smith, Wade
    Xia, Jun
    Ye, Hui
    Yang, Guang
    [J]. IEEE ACCESS, 2020, 8 (08) : 118869 - 118883
  • [6] Li L, 2020, RADIOLOGY, DOI [10.1148/radiol.2020200905, DOI 10.1148/RADIOL.2020200905]
  • [7] Lundberg SM, 2017, ADV NEUR IN, V30
  • [8] Ouyang X, 2020, Arxiv, DOI [arXiv:2005.02690, DOI 10.1109/TMI.2020.2995508, 10.1109/TMI.2020.2995508]
  • [9] "Why Should I Trust You?" Explaining the Predictions of Any Classifier
    Ribeiro, Marco Tulio
    Singh, Sameer
    Guestrin, Carlos
    [J]. KDD'16: PROCEEDINGS OF THE 22ND ACM SIGKDD INTERNATIONAL CONFERENCE ON KNOWLEDGE DISCOVERY AND DATA MINING, 2016, : 1135 - 1144
  • [10] Common pitfalls and recommendations for using machine learning to detect and prognosticate for COVID-19 using chest radiographs and CT scans
    Roberts, Michael
    Driggs, Derek
    Thorpe, Matthew
    Gilbey, Julian
    Yeung, Michael
    Ursprung, Stephan
    Aviles-Rivero, Angelica I.
    Etmann, Christian
    McCague, Cathal
    Beer, Lucian
    Weir-McCall, Jonathan R.
    Teng, Zhongzhao
    Gkrania-Klotsas, Effrossyni
    Rudd, James H. F.
    Sala, Evis
    Schonlieb, Carola-Bibiane
    [J]. NATURE MACHINE INTELLIGENCE, 2021, 3 (03) : 199 - 217