A novel fluorophore based on the coupling of AIE and ESIPT mechanisms and its application in biothiol imaging

被引：94
作者：
Chen, Qing [1 ]
Jia, Chunman [1 ,2 ]
Zhang, Yinfeng [3 ]
Du, Wei [1 ]
Wang, Yile [1 ]
Huang, Yan [4 ]
Yang, Qiuyun [1 ]
Zhang, Qi [1 ,2 ]
机构：
[1] Hainan Univ, Hainan Prov Key Lab Fine Chem, Haikou 570228, Hainan, Peoples R China
[2] Hainan Univ, Key Study Ctr, Natl Minist Educ Trop Resources Utilizat, Haikou 570228, Hainan, Peoples R China
[3] Johns Hopkins Univ, Sch Med, Dept Pathol, Baltimore, MD 21205 USA
[4] Jiangsu Univ, Sch Chem & Chem Engn, Zhenjiang 212013, Peoples R China
来源：
JOURNAL OF MATERIALS CHEMISTRY B | 2017年 / 5卷 / 37期
基金：
中国国家自然科学基金;
关键词：
PROTON-TRANSFER ESIPT; AGGREGATION-INDUCED EMISSION; LIGHT-UP PROBE; FLUORESCENT-PROBE; HYDROGEN-SULFIDE; VISUALIZATION; GLUTATHIONE; CYSTEINE;
D O I：
10.1039/c7tb02076g
中图分类号：
TB3 [工程材料学]; R318.08 [生物材料学];
学科分类号：
0805 ; 080501 ; 080502 ;
摘要：
A novel fluorophore TPE-HBT was designed based on the intersection of tetraphenylethene (TPE) and 2-(2'-hydroxyphenyl) benzothiazole (HBT). Owing to the synergistic effect of aggregation-induced emission (AIE) and excited-state intramolecular proton transfer (ESIPT) mechanisms, this fluorophore exhibits excellent performance with a high solid-state fluorescence quantum yield (Phi(F) = 0.97) and a large Stokes shift (> 200 nm). Moreover, its simple modification with the 2,4-dinitrobenzenesulfonyl group makes it suitable for biothiol imaging.
引用
收藏
页码：7736 / 7742
页数：7
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