Ring Opening of Donor-Acceptor Cyclopropanes with N-Nucle-ophiles

被引：169

作者：

Budynina, Ekaterina M. ^{[1
]}

Ivanov, Konstantin L. ^{[1
]}

Sorokin, Ivan D. ^{[1
]}

Melnikov, Mikhail Ya. ^{[1
]}

机构：

[1] Lomonosov Moscow State Univ, Dept Chem, Leninskie Gory 1-3, Moscow 119991, Russia

来源：

SYNTHESIS-STUTTGART | 2017年 / 49卷 / 14期

关键词：

donor-acceptor cyclopropanes; nucleophilic ring opening; N-nucleophiles; N-heterocycles; amines; azides; nitriles; ELECTRONICALLY EFFECTIVE CARBONYL; DOUBLY ACTIVATED CYCLOPROPANES; DIVERSITY-ORIENTED SYNTHESIS; AROMATIC AZOMETHINE IMINES; ONE-POT SYNTHESIS; LEWIS-ACID; 3+2 CYCLOADDITION; SUBSTITUTED CYCLOPROPANES; STEREOSELECTIVE-SYNTHESIS; EFFICIENT SYNTHESIS;

D O I：

10.1055/s-0036-1589021

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Ring opening of donor-acceptor cyclopropanes with various N-nucleophiles provides a simple approach to 1,3-functionalized compounds that are useful building blocks in organic synthesis, especially in assembling various N-heterocycles, including natural products. In this review, ring-opening reactions of donor-acceptor cyclopropanes with amines, amides, hydrazines, N-heterocycles, nitriles, and the azide ion are summarized.

引用

页码：3035 / 3068

页数：34

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