Recent findings from the human proteome project: opening the mass spectrometry toolbox to advance cancer diagnosis, surveillance and treatment

被引:11
作者
Cantor, David I. [1 ]
Nice, Edouard C. [2 ]
Baker, Mark S. [1 ]
机构
[1] Macquarie Univ, Fac Med & Hlth Sci, Australian Sch Adv Med, N Ryde, NSW 2109, Australia
[2] Monash Univ, Dept Biochem & Mol Biol, Clayton, Vic 3800, Australia
关键词
biology; cancer; disease; human proteome project; proteomics; LASER-DESORPTION IONIZATION; PARAFFIN-EMBEDDED TISSUE; PROSTATE-SPECIFIC ANTIGEN; HUMAN BREAST-CANCER; COLORECTAL-CANCER; OVARIAN-CANCER; HUMAN-DISEASE; MALDI-MS; QUANTITATIVE PROTEOMICS; INTERACTOME NETWORKS;
D O I
10.1586/14789450.2015.1040770
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
The Human Proteome Project stands to eclipse the Human Genome Project in terms of scope, content and interpretation. Its outputs, in conjunction with recent developments across the proteomics community, provide new tools for cancer research with the potential of providing clinically relevant insights into the disease. These collectively may guide the development of future diagnosis, surveillance and treatment strategies. Having established a robust organizational framework within the international community, the Human Proteome Organization and the proteomics community at large have made significant advances in biomarker discovery, detection, molecular imaging and in exploring tumor heterogeneity. Here, the authors discuss some developments in cancer proteomics and how they can be implemented to reduce the global burden of the disease.
引用
收藏
页码:279 / 293
页数:15
相关论文
共 125 条
[81]   The Chromosome-Centric Human Proteome Project for cataloging proteins encoded in the genome [J].
Paik, Young-Ki ;
Jeong, Seul-Ki ;
Omenn, Gilbert S. ;
Uhlen, Mathias ;
Hanash, Samir ;
Cho, Sang Yun ;
Lee, Hyoung-Joo ;
Na, Keun ;
Choi, Eun-Young ;
Yan, Fangfei ;
Zhang, Fan ;
Zhang, Yue ;
Snyder, Michael ;
Cheng, Yong ;
Chen, Rui ;
Marko-Varga, Gyorgy ;
Deutsch, Eric W. ;
Kim, Hoguen ;
Kwon, Ja-Young ;
Aebersold, Ruedi ;
Bairoch, Amos ;
Taylor, Allen D. ;
Kim, Kwang Youl ;
Lee, Eun-Young ;
Hochstrasser, Denis ;
Legrain, Pierre ;
Hancock, William S. .
NATURE BIOTECHNOLOGY, 2012, 30 (03) :221-223
[82]   Faster, Quantitative, and Accurate Precursor Acquisition Independent From Ion Count [J].
Panchaud, Alexandre ;
Jung, Sunhee ;
Shaffer, Scott A. ;
Aitchison, John D. ;
Goodlett, David R. .
ANALYTICAL CHEMISTRY, 2011, 83 (06) :2250-2257
[83]   Heterogeneity and Targeting of Pancreatic Cancer Stem Cells [J].
Penchev, Vesselin R. ;
Rasheed, Zeshaan A. ;
Maitra, Anirban ;
Matsui, William .
CLINICAL CANCER RESEARCH, 2012, 18 (16) :4277-4284
[84]  
Picotti P, 2012, NAT METHODS, V9, P555, DOI [10.1038/NMETH.2015, 10.1038/nmeth.2015]
[85]  
Picotti P, 2010, NAT METHODS, V7, P43, DOI [10.1038/nmeth.1408, 10.1038/NMETH.1408]
[86]  
Polanski M, 2006, BIOMARK INSIGHTS, V1, P1
[87]   Extracting a cellular hierarchy from high-dimensional cytometry data with SPADE [J].
Qiu, Peng ;
Simonds, Erin F. ;
Bendall, Sean C. ;
Gibbs, Kenneth D., Jr. ;
Bruggner, Robert V. ;
Linderman, Michael D. ;
Sachs, Karen ;
Nolan, Garry P. ;
Plevritis, Sylvia K. .
NATURE BIOTECHNOLOGY, 2011, 29 (10) :886-U181
[88]   A structured proteomic approach identifies 14-3-3Sigma as a novel and reliable protein biomarker in panel based differential diagnostics of liver tumors [J].
Reis, Henning ;
Puetter, Carolin ;
Megger, Dominik A. ;
Bracht, Thilo ;
Weber, Frank ;
Hoffmann, Andreas-C. ;
Bertram, Stefanie ;
Wohlschlaeger, Jeremias ;
Hagemann, Sascha ;
Eisenacher, Martin ;
Scherag, Andre ;
Schlaak, Joerg F. ;
Canbay, Ali ;
Meyer, Helmut E. ;
Sitek, Barbara ;
Baba, Hideo A. .
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS, 2015, 1854 (06) :641-650
[89]   A repository of assays to quantify 10,000 human proteins by SWATH-MS [J].
Rosenberger, George ;
Koh, Ching Chiek ;
Guo, Tiannan ;
Roest, Hannes L. ;
Kouvonen, Petri ;
Collins, Ben C. ;
Heusel, Moritz ;
Liu, Yansheng ;
Caron, Etienne ;
Vichalkovski, Anton ;
Faini, Marco ;
Schubert, Olga T. ;
Faridi, Pouya ;
Ebhardt, H. Alexander ;
Matondo, Mariette ;
Lam, Henry ;
Bader, Samuel L. ;
Campbell, David S. ;
Deutsch, Eric W. ;
Moritz, Robert L. ;
Tate, Stephen ;
Aebersold, Ruedi .
SCIENTIFIC DATA, 2014, 1
[90]  
Rubakhin SS, 2010, METHODS MOL BIOL, V656, P21, DOI 10.1007/978-1-60761-746-4_2