GC-MS quantitation of fragrance compounds suspected to cause skin reactions. 1

被引：59
作者：
Chaintreau, A
Joulain, D
Marin, C
Schmidt, CO
Vey, M
机构：
[1] Int Fragrance Assoc, Analyt Working Grp, B-1000 Brussels, Belgium
[2] Firmenich Co, CH-1211 Geneva 8, Switzerland
[3] Robertet SA, F-06131 Grasse, France
[4] Symrise, D-38112 Braunschweig, Germany
来源：
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY | 2003年 / 51卷 / 22期
关键词：
allergen; GC-MS; quantitation; skin reaction; fragrances; perfumes;
D O I：
10.1021/jf030363t
中图分类号：
S [农业科学];
学科分类号：
09 ;
摘要：
Recent changes in European legislation require monitoring of 24 volatile compounds in perfumes as they might elicit skin sensitization. This paper reports a GC-MS quantitation procedure for their determination in fragrance concentrates. GC and MS conditions were optimized for a routine use: analysis within 30 min, solvent and internal standard selection, and stock solution stability. Calibration curves were linear in the range of 2-100 mg/L with coefficients of determination in excess of 0.99. The method was tested using real perfumes spiked with known amounts of reference compounds.
引用
收藏
页码：6398 / 6403
页数：6
相关论文
共 50 条
[41]   Determination of phenolic compounds in aromatic plants by RP-HPLC and GC-MS [J].
Proestos, C ;
Sereli, D ;
Komaitis, M .
FOOD CHEMISTRY, 2006, 95 (01) :44-52
[42]   GC-MS analysis of bioactive compounds present in medicinally important Periploca hydaspidis [J].
Ullah, Rafi ;
Bakht, Jehan ;
Shah, Muhammad Raza .
PAKISTAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2019, 32 (04) :1615-1619
[43]   SPME/GC-MS characterization of volatile compounds of Iranian traditional dried Kashk [J].
Iranmanesh, Mahdieh ;
Ezzatpanah, Hamid ;
Akbari-Adergani, Behrouz ;
Torshizi, Mohammad Amir Karimi .
INTERNATIONAL JOURNAL OF FOOD PROPERTIES, 2018, 21 (01) :1067-1079
[44]   SIMULTANEOUS GC-FT-IR GC-MS ANALYSIS FOR ISOMER-SPECIFIC IDENTIFICATION AND QUANTITATION OF COMPLEX MIXTURE COMPONENTS [J].
SMYRL, NR ;
HEMBREE, DM ;
DAVIS, WE ;
WILLIAMS, DM ;
VANCE, JC .
APPLIED SPECTROSCOPY, 1992, 46 (02) :277-282
[45]   Determination of Volatile Organic Compounds in Human Skin Gas by GC/MS [J].
Hisanaga, Mahoro ;
Tsuda, Takao ;
Ohkuwa, Tetsuo ;
Ito, Hiroshi .
BUNSEKI KAGAKU, 2012, 61 (01) :57-61
[46]   GC-MS quantitation of benzoic and aralkyl carboxylic acids as their trimethylsilyl derivatives:: in model solutions I. [J].
Molnár-Perl, I ;
Horváth, K ;
Bartha, R .
CHROMATOGRAPHIA, 1998, 48 (1-2) :101-110
[47]   Assessment of oxidation compounds in oaked Chardonnay wines: A GC-MS and 1H NMR metabolomics approach [J].
Pinto, Joana ;
Oliveira, Ana Sofia ;
Azevedo, Joana ;
De Freitas, Victor ;
Lopes, Paulo ;
Roseira, Isabel ;
Cabral, Miguel ;
de Pinho, Paula Guedes .
FOOD CHEMISTRY, 2018, 257 :120-127
[48]   Characterization of the Volatile Compounds of Zhenba Bacon at Different Process Stages Using GC-MS and GC-IMS [J].
Xi, Linjie ;
Zhang, Jing ;
Wu, Ruixiao ;
Wang, Tian ;
Ding, Wu .
FOODS, 2021, 10 (11)
[49]   Identification of organic arsenic, tin, antimony and tellurium compounds in environmental samples by GC-MS [J].
Kösters, J ;
Diaz-Bone, RA ;
Planer-Friedrich, B ;
Rothweiler, B ;
Hirner, AV .
JOURNAL OF MOLECULAR STRUCTURE, 2003, 661 :347-356
[50]   Investigation of bioactive phytochemical compounds of the Ethiopian medicinal plant using GC-MS and FTIR [J].
Endris, Yassin Adem ;
Abdu, Kedir Yesuf ;
Abate, Solomon Getachew .
HELIYON, 2024, 10 (15)
12345