GC-MS quantitation of fragrance compounds suspected to cause skin reactions. 1

被引:60
作者
Chaintreau, A
Joulain, D
Marin, C
Schmidt, CO
Vey, M
机构
[1] Int Fragrance Assoc, Analyt Working Grp, B-1000 Brussels, Belgium
[2] Firmenich Co, CH-1211 Geneva 8, Switzerland
[3] Robertet SA, F-06131 Grasse, France
[4] Symrise, D-38112 Braunschweig, Germany
关键词
allergen; GC-MS; quantitation; skin reaction; fragrances; perfumes;
D O I
10.1021/jf030363t
中图分类号
S [农业科学];
学科分类号
09 ;
摘要
Recent changes in European legislation require monitoring of 24 volatile compounds in perfumes as they might elicit skin sensitization. This paper reports a GC-MS quantitation procedure for their determination in fragrance concentrates. GC and MS conditions were optimized for a routine use: analysis within 30 min, solvent and internal standard selection, and stock solution stability. Calibration curves were linear in the range of 2-100 mg/L with coefficients of determination in excess of 0.99. The method was tested using real perfumes spiked with known amounts of reference compounds.
引用
收藏
页码:6398 / 6403
页数:6
相关论文
共 50 条
[21]   Determination of Organotin Compounds in Water Soluble Paints and Adhesives by GC-MS [J].
Kawakami, Tsuyoshi ;
Isama, Kazuo ;
Nakashima, Harunobu ;
Ooshima, Tomoko ;
Tsuchiya, Toshie ;
Matsuoka, Atsuko .
YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 2010, 130 (02) :223-235
[22]   Identification of buckwheat (Fagopyrum esculentum Moench) aroma compounds with GC-MS [J].
Janes, Damjan ;
Kantar, Dragana ;
Kreft, Samo ;
Prosen, Helena .
FOOD CHEMISTRY, 2009, 112 (01) :120-124
[23]   Determination of volatile compounds in cows' milk using headspace GC-MS [J].
Toso, B ;
Procida, G ;
Stefanon, B .
JOURNAL OF DAIRY RESEARCH, 2002, 69 (04) :569-577
[24]   Determination of selected organoarsenic compounds by SPME/GC-MS in aquatic samples [J].
Czaplicka, Marianna ;
Jaworek, Katarzyna ;
Klyta, Justyna .
DESALINATION AND WATER TREATMENT, 2019, 172 :386-394
[25]   Analysis of Volatile Flavor Compounds in Huizhou Preserved Vegetable by GC-MS [J].
Liu, Yuping ;
Miao, Zhiwei ;
Yang, Junkai ;
Guan, Wei ;
Sun, Baoguo .
MEDICAL MATERIALS AND ENGINEERING, 2012, 140 :258-+
[26]   Analysis of volatile floral fragrance components of Camellia yuhsienensis Hu by HS-SPME/GC-MS [J].
Yuan, Yaqi ;
Tan, XinJian ;
Zhong, Qiuping ;
Ge, Xiaoning ;
Yan, Chao ;
Guo, Hongyan ;
Zou, Yuling ;
Cao, Linqing ;
Wang, Jinfeng ;
Zhou, Youcheng ;
Yuan, YongJiao .
FLAVOUR AND FRAGRANCE JOURNAL, 2024, 39 (06) :370-383
[27]   Comparison of Flavor Compounds in Fresh and Pickled Bamboo Shoots by GC-MS and GC-Olfactometry [J].
Zhen, Jiong ;
Zhan, Fusheng ;
Zhou, Chunhong ;
Kan, Jianquan .
FOOD SCIENCE AND TECHNOLOGY RESEARCH, 2014, 20 (01) :129-138
[28]   GC-MS quantitation of benzoic and aralkyl carboxylic acids as their trimethylsilyl derivatives: In model solution I [J].
I. Molnár-Perl ;
K. Horváth ;
R. Bartha .
Chromatographia, 1998, 48 :101-110
[29]   Reliable quantitation of β-hydroxyethoxyacetic acid in human urine by an isotope-dilution GC-MS procedure [J].
Eckert, Elisabeth ;
Gries, Wolfgang ;
Goeen, Thomas ;
Leng, Gabriele .
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2013, 935 :80-84
[30]   A GC-MS method for the detection and quantitation of ten major drugs of abuse in human hair samples [J].
Orfanidis, A. ;
Mastrogianni, O. ;
Koukou, A. ;
Psarros, G. ;
Gika, H. ;
Theodoridis, G. ;
Raikos, N. .
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2017, 1047 :141-150