Selecting reactions and reactants using a switchable rotaxane organocatalyst with two different active sites

被引：110

作者：

Beswick, Jack ^{[1
]}

Blanco, Victor ^{[1
]}

De Bo, Guillaume ^{[1
]}

Leigh, David A. ^{[1
]}

Lewandowska, Urszula ^{[1
]}

Lewandowski, Bartosz ^{[1
]}

Mishiro, Kenji ^{[1
]}

机构：

[1] Univ Manchester, Sch Chem, Manchester M13 9PL, Lancs, England

来源：

CHEMICAL SCIENCE | 2015年 / 6卷 / 01期

基金：

英国工程与自然科学研究理事会;

关键词：

SMALL-MOLECULE; ASYMMETRIC AMINOCATALYSIS; MICHAEL ADDITION; LIGHT; CATALYSIS; FUNCTIONALIZATION; NANOSWITCH; ALDEHYDES; SHUTTLE; MANNICH;

D O I：

10.1039/c4sc03279a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The activation mode of a rotaxane-based organocatalyst with both secondary amine and squaramide catalytic units can be switched with acid or base. The macrocycle blocks whichever of the catalytic sites it is positioned over. The switchable rotaxane catalyst generates different products from a mixture of three building blocks according to the location of the macrocyclic ring in the rotaxane.

引用

页码：140 / 143

页数：4

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