Efficient synthesis of novel spiro[indole-3,6′-pyrano[2,3-d][1,3]thiazolo[3,2-a]pyrimidine derivatives through an organobase-catalyzed, three-component reaction

被引：25

作者：

Esmaeili, Abbas Ali ^{[1
]}

Amini-Ghalandarabad, Saeid ^{[2
]}

Mesbah, Fariba ^{[2
]}

Tasmimi, Masoud ^{[2
]}

Izadyar, Mohammad ^{[1
]}

Fakhari, Ali Reza ^{[3
]}

Salimi, Ali Reza ^{[1
]}

机构：

[1] Ferdowsi Univ Mashhad, Dept Chem, Mashhad, Iran

[2] Univ Birjand, Dept Chem, Birjand, Iran

[3] Shahid Beheshti Univ, Dept Chem, Fac Sci, GC, Tehran, Iran

来源：

TETRAHEDRON | 2015年 / 71卷 / 16期

关键词：

Spirooxindole; Malononitrile; Three-component reactions; Pyranothiazolopyrimidine; ONE-POT SYNTHESIS; MULTICOMPONENT REACTIONS; C-H; CONSTRUCTION; PYRIMIDINE; ISATIN; THIAZOLOPYRIMIDINES; SPIROOXINDOLES; OXINDOLES; ANALOGS;

D O I：

10.1016/j.tet.2015.01.055

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A fast and convenient protocol for the synthesis of novel spirooxindole derivatives in excellent yields was developed by the three-component reactions of malononitrile, isatin, and 2,3-dihydro-5H-[1,3]thiazolo [3,2-a]pyrimidine-5,7(6H)-dione in the presence of diisopropylethylamine. (C) 2015 Elsevier Ltd. All rights reserved.

引用

收藏

页码：2458 / 2462

页数：5

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