Monitoring ADP and ATP in vivo using a fluorescent Ga(III)-probe complex

被引:23
作者
Zhang, Xinyu [1 ]
Jiang, Yuqian [1 ]
Xiao, Nao [1 ]
机构
[1] Capital Med Univ, Sch Pharmaceut Sci, Engn Res Ctr Endogenous Prophylact,Minist Educ Ch, Beijing Area Major Lab Peptide & Small Mol Drugs, Beijing 100069, Peoples R China
基金
北京市自然科学基金;
关键词
TURN-ON; AQUEOUS-SOLUTION; PROBE; IONS; GA3+; GALLIUM; SENSOR; BENZOTHIAZOLE; PYROPHOSPHATE; RECOGNITION;
D O I
10.1039/c8cc06311g
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A naphthol-based sensor (L) was designed and synthesized for the specific recognition of Ga3+ using fluorescence enhancement. An in situ generated L-Ga3+ ensemble detected ADP and ATP more selectively through a fluorescence "switch off" response, which was confirmed both in cells and in adult zebrafish.
引用
收藏
页码:12812 / 12815
页数:4
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