ONE-POT SYNTHESIS OF NEW BENZOIMIDAZOLINE DERIVATIVES PROMOTED BY POTASSIUM CARBONATE

被引:0
|
作者
Xue, Meng-Wei [1 ]
Zhou, Hong [1 ]
Yang, Jing-Jing [1 ]
Li, Jian [1 ]
Liu, Shao-Xian [1 ]
Zhang, Dun-Lin [1 ]
机构
[1] Nanjing Xiaozhuang Univ, Sch Biochem & Environm Engn, Nanjing 211171, Jiangsu, Peoples R China
关键词
Benzimidazole Derivative; One-Pot Reaction; BENZIMIDAZOLE DERIVATIVES; PROGRESS;
D O I
10.3987/COM-14-13110
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
An efficient method for synthesis of new benzoimidazoline derivatives has been accomplished via a one-pot reaction of aromatic aldehyde, o-phenylenediamine / 4-Cl-o-phenylenediamine and acetic anhydride promoted by K2CO3. In this method, although aryl substituted aldehydes with electron-releasing substituents did not work in the reaction, a series of aryl substituted aldehydes carrying electron-withdrawing substituents gave the corresponding benzoimidazoline derivatives with good yields of 62 % - 93 %.
引用
收藏
页码:2777 / 2785
页数:9
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