Isolation and characterization of atypical Listeria monocytogenes associated with a canine urinary tract infection

被引:7
作者
Palerme, Jean-Sebastien [1 ]
Pan, Po Ching [1 ]
Parsons, Cameron T. [2 ]
Kathariou, Sophia [2 ]
Ward, Todd J. [4 ]
Jacob, Megan E. [3 ]
机构
[1] North Carolina State Univ, Dept Clin Sci, Raleigh, NC USA
[2] North Carolina State Univ, Dept Food Bioproc & Nutr Sci, Raleigh, NC USA
[3] North Carolina State Univ, Dept Populat Hlth & Pathobiol, Raleigh, NC USA
[4] ARS, USDA, Peoria, IL USA
关键词
Canine listeriosis; canine urinary tract infection; Listeria monocytogenes; DOGS;
D O I
10.1177/1040638716661381
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
Listeria monocytogenes, a well-described cause of encephalitis and abortion in ruminants and of food-borne illness in humans, is rarely associated with disease in companion animals. A case of urinary tract infection associated with an atypical, weakly hemolytic L. monocytogenes strain is described in a diabetic dog. The serotype of the L. monocytogenes isolate was determined to be 1/2a (3a), with the multilocus genotyping pattern 2.72_1/2a. A nucleotide substitution (Gly145Asp) was detected at residue 145 in the promoter prfA region. This residue is within the critical helix-turn-helix motif of PrfA. The source of the L. monocytogenes strain remains unknown, and the dog recovered after a 4-week course of cephalexin (30 mg/kg orally twice daily).
引用
收藏
页码:604 / 607
页数:4
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