Secondary angiosarcoma: A fatal complication of chronic lymphedema

被引：13

作者：

Farzaliyev, Farhad ^{[1
]}

Hamacher, Rainer ^{[2
]}

Steinau, Hans-Ulrich ^{[1
]}

Bertram, Stefanie ^{[3
]}

Podleska, Lars Erik ^{[4
]}

机构：

[1] Univ Essen Duisburg, Univ Hosp Essen, Dept Gen Visceral & Transplantat Surg, Div Plast Reconstruct & Hand Surg, Hufelandstr 55, D-45147 Essen, Germany

[2] Univ Duisburg Essen, Univ Hosp Essen, West German Canc Ctr, Dept Med Oncol,Sarcoma Ctr, Essen, Germany

[3] Univ Duisburg Essen, Univ Hosp Essen, Inst Pathol & Neuropathol, Essen, Germany

[4] Univ Essen Duisburg, Univ Hosp Essen, Dept Tumor Orthoped & Sarcoma Surg, Essen, Germany

来源：

JOURNAL OF SURGICAL ONCOLOGY | 2020年 / 121卷 / 01期

关键词：

hyperthermic isolated limb perfusion; multimodal therapy; Stewart-Treves Syndrome; STEWART-TREVES SYNDROME; CUTANEOUS ANGIOSARCOMA; BREAST; DISSECTION; SURGERY;

D O I：

10.1002/jso.25598

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Secondary Angiosarcoma (Stewart-Treves Syndrome) is a rare malignant cutaneous lesion, which arises in chronic lymphedema of the extremity, often observed after breast cancer treatment. We reviewed the history and the oncological outcome of two patients with this disease. Multimodal therapy including hyperthermic isolated limb perfusion with TNF-alpha and Melphalan, combined with radical resection of the affected skin and subcutaneous tissue including the fascia, with large safety margins may probably lead to better survival.

引用

页码：85 / 90

页数：6

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