Asterogynins: Secondary Metabolites from a Costa Rican Endophytic Fungus

被引：41

作者：

Cao, Shugeng ^{[1
]}

Ross, Leila ^{[1
]}

Tamayo, Giselle

Clardy, Jon ^{[1
]}

机构：

[1] Harvard Univ, Sch Med, Dept Biol Chem & Mol Pharmacol, Boston, MA 02115 USA

来源：

ORGANIC LETTERS | 2010年 / 12卷 / 20期

关键词：

PLASMODIUM-FALCIPARUM; WORTMANNIN; VIRIDIOL;

D O I：

10.1021/ol101972g

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An endophytic fungus isolated from the small palm Asterogyne martiona produced two unusual steroid-like metabolites, asterogynin A (1) and asterogynin B (2), along with the known compounds viridiol (3) and vindin (4) Asterogynins A and B were characterized by NMR and MS spectroscopic analysis

引用

页码：4661 / 4663

页数：3

共 12 条

[1] Chaperoning a cellular upheaval in malaria:: Heat shock proteins in Plasmodium falciparum
Acharya, Pragyan
Kumar, Ranjit
Tatu, Utpal
[J]. MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 2007, 153 (02) : 85 - 94
[2] Laschiatrion, a new antifungal agent from a Favolaschia species (Basidiomycetes) active against human pathogens
Anke, T
Werle, A
Kappe, RB
Sterner, O
[J]. JOURNAL OF ANTIBIOTICS, 2004, 57 (08) : 496 - 501
[3] Synthesis of fluorescent derivatives of wortmannin and demethoxyviridin as probes for phosphatidylinositol 3-kinase
Giner, JL
Kehbein, KA
Cook, JA
Smith, MC
Vlahos, CJ
Badwey, JA
[J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2006, 16 (09) : 2518 - 2521
[4] THE FUNGAL DIMENSION OF BIODIVERSITY - MAGNITUDE, SIGNIFICANCE, AND CONSERVATION
HAWKSWORTH, DL
[J]. MYCOLOGICAL RESEARCH, 1991, 95 : 641 - 655
[5] Henkel T, 1999, ANGEW CHEM INT EDIT, V38, P643, DOI 10.1002/(SICI)1521-3773(19990301)38:5<643::AID-ANIE643>3.0.CO
[6] 2-G
[7] CONVERSION OF VIRIDIN TO VIRIDIOL BY VIRIDIN-PRODUCING FUNGI
JONES, RW
HANCOCK, JG
[J]. CANADIAN JOURNAL OF MICROBIOLOGY, 1987, 33 (11) : 963 - 966
[8] The heat shock protein 90 of Plasmodium falciparum and antimalarial activity of its inhibitor, geldanamycin -: art. no. 30
Kumar, R
Musiyenko, A
Barik, S
[J]. MALARIA JOURNAL, 2003, 2 (1)
[9] PIMM SL, 1995, SCIENCE, V269, P374
[10] Novel ring B abeo-sterols as growth inhibitors of Mycobacterium tuberculosis isolated from a Caribbean Sea sponge, Svenzea zeai
Wei, Xiaomei
Rodriguez, Abimael D.
Wang, Yuehong
Franzblau, Scott G.
[J]. TETRAHEDRON LETTERS, 2007, 48 (50) : 8851 - 8854

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