A simple fluorescein derived colorimetric and fluorescent 'off-on' sensor for the detection of hypochlorite

被引：27

作者：

Jin, Lei ^{[1
,2
]}

Xu, Mengyi ^{[1
]}

Jiang, Hua ^{[1
]}

Wang, Wenling ^{[1
]}

Wang, Qingming ^{[1
]}

机构：

[1] Yancheng Teachers Univ, Sch Pharm, Jiangsu Prov Key Lab Coastal Wetland Bioresources, Yancheng 224051, Jiangsu, Peoples R China

[2] Nanjing Univ Technol, Coll Biotechnol & Pharmaceut Engn, Nanjing 210009, Jiangsu, Peoples R China

来源：

ANALYTICAL METHODS | 2018年 / 10卷 / 37期

关键词：

LIVING CELLS; SELECTIVE DETECTION; HYDROGEN-PEROXIDE; OXIDATIVE STRESS; AQUEOUS-SOLUTION; FAST-RESPONSE; PROBE; ACID; MYELOPEROXIDASE; WATER;

D O I：

10.1039/c8ay01489b

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

In this work, we have successfully provided a novel strategy to probe for ClO-. The strategy is based on a specific reaction promoted by ClO-: namely, hypochlorite oxidizes the amino group in probe 1 to an imine. Interestingly, in the presence of ClO-, a colorless solution of probe 1 turned pink with a maximum absorption band at 479 nm, and a 150-fold fluorescence enhancement at 553 nm was found. Probe 1 is highly selective to ClO- among other anions with a detection limit of 0.023 M. The membrane-permeable probe 1 was successfully demonstrated for monitoring ClO- in cultured HeLa cells. Therefore, probe 1 can be used for detection in practical samples. Probe 1 developed herein makes possible the use of organic complexes containing amines for designing fluorescence probes for ClO-.

引用

页码：4562 / 4569

页数：8

共 35 条

[11]

HARRISON JE, 1976, J BIOL CHEM, V251, P1371

[12] A fast response fluorescence probe specific for hypochlorous acid detection and its applications in bioimaging [J].

Jia, Hongmin ;

Xia, Shuhe ;

Feng, Huan ;

Meng, Qingtao ;

Duan, Chengchen ;

Zhang, Zhiqiang ;

Zhang, Run .

ORGANIC & BIOMOLECULAR CHEMISTRY, 2018, 16 (12) :2074-2082

[13] Fluorescence probe for hypochlorous acid in water and its applications for highly lysosome-targetable live cell imaging [J].

Jiao, Xiaojie ;

Liu, Chang ;

Wang, Qing ;

Huang, Kun ;

He, Song ;

Zhao, Liancheng ;

Zeng, Xianshun .

ANALYTICA CHIMICA ACTA, 2017, 969 :49-56

[14] Dual-Functional Fluorescein-Based Chemosensor for Chromogenic Detection of Fe3+ and Fluorgenic Detection of HOCl [J].

Jin, Xilang ;

Wu, Xianglong ;

Liu, Liu ;

Wang, Zenghui ;

Xie, Pu ;

Ma, Aijie ;

Zhou, Hongwei ;

Chen, Weixing .

JOURNAL OF FLUORESCENCE, 2017, 27 (06) :2111-2117

[15] An exogenous marker: A novel approach for the characterization of oxidative stress [J].

Khatib, Soliman ;

Musa, Ramadan ;

Vaya, Jacob .

BIOORGANIC & MEDICINAL CHEMISTRY, 2007, 15 (11) :3661-3666

[16] Myeloperoxidase: friend and foe [J].

Klebanoff, SJ .

JOURNAL OF LEUKOCYTE BIOLOGY, 2005, 77 (05) :598-625

[17] Development of an Si-Rhodamine-Based Far-Red to Near-Infrared Fluorescence Probe Selective for Hypochlorous Acid and Its Applications for Biological Imaging [J].

Koide, Yuichiro ;

Urano, Yasuteru ;

Hanaoka, Kenjiro ;

Terai, Takuya ;

Nagano, Tetsuo .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2011, 133 (15) :5680-5682

[18] Rapid Detection of Hydrogen Peroxide Based on Aggregation Induced Ratiometric Fluorescence Change [J].

Li, Guoping ;

Zhu, Dongjian ;

Liu, Qing ;

Xue, Lin ;

Jiang, Hua .

ORGANIC LETTERS, 2013, 15 (04) :924-927

[19] A highly selective and sensitive photoinduced electron transfer (PET) based HOCl fluorescent probe in water and its endogenous imaging in living cells [J].

Liang, Lijuan ;

Liu, Chang ;

Jiao, Xiaojie ;

Zhao, Liancheng ;

Zeng, Xianshun .

CHEMICAL COMMUNICATIONS, 2016, 52 (51) :7982-7985

[20] Continuous detection of hypochlorous acid/hypochlorite for water quality monitoring and control [J].

Ordeig, O ;

Mas, R ;

Gonzalo, J ;

Del Campo, FJ ;

Muñoz, FJ ;

de Haro, C .

ELECTROANALYSIS, 2005, 17 (18) :1641-1648

← 1 2 3 4 →