Multidimensional statistical analysis of PTR-MS breath samples: A test study on irradiation detection

被引:21
作者
Fedrigo, Mattia [1 ]
Hoeschen, Christoph [1 ]
Oeh, Uwe [1 ]
机构
[1] Helmholtz Zentrum Munchen, German Res Ctr Environm Hlth GmbH, D-85764 Neuherberg, Germany
关键词
Multidimensional analysis; PTR-MS; Breath gas VOC; Detection of exposure; REACTION-MASS-SPECTROMETRY; VOLATILE ORGANIC-COMPOUNDS; GAS-ANALYSIS; ISOPRENE; METHANOL; AIR;
D O I
10.1016/j.ijms.2010.06.011
中图分类号
O64 [物理化学(理论化学)、化学物理学]; O56 [分子物理学、原子物理学];
学科分类号
070203 ; 070304 ; 081704 ; 1406 ;
摘要
A multidimensional statistical analysis of data obtained from breath gas measurements with Proton Transfer Reaction-Mass Spectrometry (PTR-MS) is proposed, based on a chemical-diffusion equilibrium approach. The proposed methodology is developed and demonstrated on the problem of detecting exposure of human beings to ionizing radiation. It could be applied to a general family of non-invasive, high-throughput, breath gas based detection strategies, like for instance a breath gas test for early diagnosis of lung cancer. (C) 2010 Elsevier B.V. All rights reserved.
引用
收藏
页码:13 / 20
页数:8
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