Cancer and atrial fibrillation: Epidemiology, mechanisms, and anticoagulation treatment

被引：26

作者：

Menichelli, Danilo ^{[1
]}

Vicario, Tommasa ^{[2
,3
]}

Ameri, Pietro ^{[4
,6
]}

Toma, Matteo ^{[4
,6
]}

Violi, Francesco ^{[1
,5
]}

Pignatelli, Pasquale ^{[1
,5
]}

Pastori, Daniele ^{[1
]}

机构：

[1] Sapienza Univ Rome, Dept Clin Internal Anesthesiol & Cardiovasc Sci, Rome, Italy

[2] Sapienza Univ Rome, Dept Gen Surg & Surg Specialties Paride Stefanini, Rome, Italy

[3] Policlin Tor Vergata Hosp, Emergency Dept, Rome, Italy

[4] IRCCS Osped Policlin San Martino, Cardiovasc Dis Unit, Genoa, Italy

[5] Mediterranea Cardioctr, Naples, Italy

[6] Univ Genoa, Dept Internal Med, Genoa, Italy

来源：

PROGRESS IN CARDIOVASCULAR DISEASES | 2021年 / 66卷

关键词：

Atrial fibrillation; Cancer; Oral anticoagulants; Chemotherapy; Radiotherapy; DOACs; DIRECT ORAL ANTICOAGULANTS; OXIDATIVE STRESS; RISK-FACTORS; CARDIOVASCULAR TOXICITY; POSITION PAPER; 2016; ESC; WARFARIN; SAFETY; THROMBOCYTOPENIA; THROMBOEMBOLISM;

D O I：

10.1016/j.pcad.2021.04.004

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Cancer patients are at an increased risk of developing atrial fibrillation (AF) and thrombosis. However, the management of anticoagulation in patients with both diseases may be challenging, and data on these patients are lacking. We summarize the current evidence on the incidence and prevalence of cancer in AF and vice versa and provide some practical considerations on the management of oral anticoagulation in specific clinical situations. Low-molecular weight heparins are not approved for thromboprophylaxis in AF, and management of warfarin can be difficult. The use of direct oral anticoagulants may be particularly attractive for their rapid onset/ offset action and lower bleeding risk. (c) 2021 Elsevier Inc. All rights reserved.

引用

页码：28 / 36

页数：9

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