Setting Global Standards for Stem Cell Research and Clinical Translation: The 2016 ISSCR Guidelines

被引：158

作者：

Daley, George Q. ^{[1
,2
]}

Hyun, Insoo ^{[3
]}

Apperley, Jane F. ^{[4
]}

Barker, Roger A. ^{[5
]}

Benvenisty, Nissim ^{[6
]}

Bredenoord, Annelien L. ^{[7
]}

Breuer, Christopher K. ^{[8
]}

Caulfield, Timothy ^{[9
]}

Cedars, Marcelle I. ^{[10
]}

Frey-Vasconcells, Joyce ^{[11
]}

Heslop, Helen E. ^{[12
,13
]}

Jin, Ying ^{[14
]}

Lee, Richard T. ^{[15
]}

McCabe, Christopher ^{[16
]}

Munsie, Megan ^{[17
]}

Murry, Charles E. ^{[18
,19
,20
]}

Piantadosi, Steven ^{[21
]}

Rao, Mahendra ^{[22
,23
]}

Rooke, Heather M. ^{[24
]}

Sipp, Douglas ^{[25
,26
]}

Studer, Lorenz ^{[27
]}

Sugarman, Jeremy ^{[28
]}

Takahashi, Masayo ^{[29
]}

Zimmerman, Mark ^{[30
]}

Kimmelman, Jonathan ^{[31
]}

机构：

[1] Boston Childrens Hosp, Div Hematol Oncol, Boston, MA 02115 USA

[2] Dana Farber Canc Inst, Boston, MA 02115 USA

[3] Case Western Reserve Univ, Dept Bioeth, Sch Med, Cleveland, OH 44106 USA

[4] Hammersmith Hosp, Univ London Imperial Coll Sci Technol & Med, Ctr Hematol, Du Cane Rd, London W12 0NN, England

[5] John Geest Ctr Brain Repair, Dept Clin Neurosci, Cambridge CB2 0PY, England

[6] Hebrew Univ Jerusalem, Azrieli Ctr Stem Cells & Genet Res, Dept Genet, IL-91904 Jerusalem, Israel

[7] Univ Med Ctr Utrecht, Julius Ctr, Dept Med Humanities, POB 85500, NL-3508 GA Utrecht, Netherlands

[8] Nationwide Childrens Hosp, Ctr Cardiovasc Res, Columbus, OH 43215 USA

[9] Univ Alberta, Hlth Law Inst, Edmonton, AB T6G 2H5, Canada

[10] Univ Calif San Francisco, Sch Med, San Francisco, CA 94158 USA

[11] Frey Vasconcells Consulting, Sykesville, MD 21784 USA

[12] Houston Methodist Hosp, Ctr Cell & Gene Therapy, Baylor Coll Med, Houston, TX 77030 USA

[13] Texas Childrens Hosp, Houston, TX 77030 USA

[14] Chinese Acad Sci, Inst Hlth Sci, Shanghai JiaoTong Univ, Sch Med,Shanghai Inst Biol Sci, Shanghai 200025, Peoples R China

[15] Harvard Univ, Harvard Dept Stem Cell & Regenerat Biol, Cambridge, MA 02138 USA

[16] Univ Alberta, Dept Emergency Med, Edmonton, AB T6G 2B7, Canada

[17] Univ Melbourne, Dept Anat & Neurosci, Educat Eth Law & Community Awareness Unit, Stem Cells Australia, Melbourne, Vic 3010, Australia

[18] Univ Washington, Dept Pathol, Inst Stem Cell & Regenerat Med, Ctr Cardiovasc Biol, Seattle, WA 98109 USA

[19] Univ Washington, Dept Bioengn, Inst Stem Cell & Regenerat Med, Ctr Cardiovasc Biol, Seattle, WA 98109 USA

[20] Univ Washington, Dept Med Cardiol, Inst Stem Cell & Regenerat Med, Ctr Cardiovasc Biol, Seattle, WA 98109 USA

[21] Cedars Sinai Med Ctr, Samuel Oschin Comprehens Canc Inst, Los Angeles, CA 90048 USA

[22] New York Stem Cell Fdn Res Inst, New York, NY 10023 USA

[23] Q Therapeut, Salt Lake City, UT 84108 USA

[24] Int Soc Stem Cell Res, Skokie, IL 60077 USA

[25] RIKEN, Ctr Dev Biol, Kobe, Hyogo 6500047, Japan

[26] Keio Univ, Sch Med, Tokyo 1608582, Japan

[27] Mem Sloan Kettering Canc Ctr, Ctr Stem Cell Biol, New York, NY 10065 USA

[28] Johns Hopkins Berman Inst Bioeth, Baltimore, MD 21205 USA

[29] RIKEN, Ctr Dev Biol, Kobe, Hyogo 6500047, Japan

[30] ViaCyte, San Diego, CA 92121 USA

[31] McGill Univ, Biomed Eth Unit, Montreal, PQ H3A 1X1, Canada

来源：

STEM CELL REPORTS | 2016年 / 6卷 / 06期

基金：

英国医学研究理事会;

关键词：

D O I：

10.1016/j.stemcr.2016.05.001

中图分类号：

Q813 [细胞工程];

学科分类号：

摘要：

The International Society for Stem Cell Research (ISSCR) presents its 2016 Guidelines for Stem Cell Research and Clinical Translation (ISSCR, 2016). The 2016 guidelines reflect the revision and extension of two past sets of guidelines (ISSCR, 2006; ISSCR, 2008) to address new and emerging areas of stem cell discovery and application and evolving ethical, social, and policy challenges. These guidelines provide an integrated set of principles and best practices to drive progress in basic, translational, and clinical research. The guidelines demand rigor, oversight, and transparency in all aspects of practice, providing confidence to practitioners and public alike that stem cell science can proceed efficiently and remain responsive to public and patient interests. Here, we highlight key elements and recommendations in the guidelines and summarize the recommendations and deliberations behind them.

引用

页码：787 / 797

页数：11

共 19 条

[1]

ACOG Committee on Ethics, 2006, Obstet Gynecol, V108, P1305

[2] Donating embryos for human embryonic stem cell (hESC) research: a committee opinion [J].

不详 .

FERTILITY AND STERILITY, 2013, 100 (04) :935-939

[3]

Caulfield T., 2016, SCIENCE

[4]

Deglincerti A., 2016, NATURE

[5]

ESHRE Taskforce on ethics and law, 2001, HUM REPROD, V17, P1409

[6] Position Statement on the Provision and Procurement of Human Eggs for Stem Cell Research [J].

Haimes, Erica ;

Skene, Loane ;

Ballantyne, Angela J. ;

Caulfield, Timothy ;

Goldstein, Lawrence S. ;

Hyun, Insoo ;

Kimmelman, Jonathan ;

Robert, Jason S. ;

Roxland, Beth E. ;

Scott, Christopher T. ;

Solbakk, Jan Helge ;

Sugarman, Jeremy ;

Taylor, Patrick L. ;

Testa, Giuseppe .

CELL STEM CELL, 2013, 12 (03) :285-291

[7] Revisit the 14-day rule [J].

Hyun, Insoo ;

Wilkerson, Amy ;

Johnston, Josephine .

NATURE, 2016, 533 (7602) :169-171

[8]

International Society for Stem Cell Research (ISSCR), 2008, GUID CLIN TRANSL STE

[9]

International Society for Stem Cell Research (ISSCR), 2006, GUID COND HUM EMBR S

[10]

ISSCR, 2016, Guidelines for Stem Cell Research and Clinical Translation

← 1 2 →