Phenome-wide association analysis suggests the APOL1 linked disease spectrum primarily drives kidney-specific pathways

被引:0
作者
Bajaj, Archna [1 ]
Ihegword, Andrea [2 ]
Qiu, Chengxiang [1 ,3 ]
Small, Aeron M. [4 ,5 ]
Wei, Wei-Qi [6 ]
Bastarache, Lisa [6 ]
Feng, QiPing [2 ]
Kember, Rachel L. [7 ,8 ]
Risman, Marjorie [1 ]
Bloom, Roy D. [1 ,3 ]
Birtwell, David L. [9 ]
Williams, Heather [9 ]
Shaffer, Christian M. [2 ]
Chen, Jinbo [10 ]
Denny, Joshua C. [2 ,6 ]
Rader, Daniel J. [1 ,4 ,7 ]
Stein, C. Michael [2 ,12 ]
Damrauer, Scott M. [13 ,14 ]
Susztak, Katalin [1 ,3 ,4 ]
机构
[1] Univ Penn, Dept Med, Philadelphia, PA 19104 USA
[2] Vanderbilt Univ, Med Ctr, Dept Med, Nashville, TN USA
[3] Univ Penn, Dept Med, Renal Elect & Hypertens Div, Perelman Sch Med, Philadelphia, PA 19104 USA
[4] Univ Penn, Cardiovasc Inst, Perelman Sch Med, Philadelphia, PA 19104 USA
[5] Yale New Haven Med Ctr, Dept Med, 20 York St, New Haven, CT 06504 USA
[6] Vanderbilt Univ, Med Ctr, Dept Biomed Informat, Nashville, TN USA
[7] Univ Penn, Dept Genet, Philadelphia, PA 19104 USA
[8] Corporal Michael Crescenz Vet Affairs Med Ctr, VISN Mental Illness Res Educ & Clin Ctr 4, Philadelphia, PA USA
[9] Univ Penn, Perelman Sch Med, Inst Translat Med & Therapeut, Philadelphia, PA 19104 USA
[10] Univ Penn, Perelman Sch Med, Ctr Clin Epidemiol & Biostat, Philadelphia, PA 19104 USA
[11] Regeneron Genet Ctr, Tarrytown, NY USA
[12] Vanderbilt Univ, Dept Pharmacol, Nashville, TN USA
[13] Univ Penn, Dept Surg, Philadelphia, PA 19104 USA
[14] Corporal Michael Crescenz Vet Affairs Med Ctr, Dept Surg, Philadelphia, PA USA
基金
美国国家卫生研究院;
关键词
STAGE RENAL-DISEASE; RISK VARIANTS; CARDIOVASCULAR-DISEASE; EGFR DECLINE; GENOTYPE; RACE;
D O I
暂无
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:1032 / 1041
页数:10
相关论文
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