Alcohol e-Help: study protocol for a web-based self-help program to reduce alcohol use in adults with drinking patterns considered harmful, hazardous or suggestive of dependence in middle-income countries

被引：11

作者：

Schaub, Michael P. ^{[1
]}

Tiburcio, Marcela ^{[2
]}

Martinez, Nora ^{[3
]}

Ambekar, Atul ^{[4
,5
]}

Balhara, Yatan Pal Singh ^{[4
,5
]}

Wenger, Andreas ^{[1
]}

Monezi Andrade, Andre Luiz ^{[6
]}

Padruchny, Dzianis ^{[7
]}

Osipchik, Sergey ^{[8
]}

Gehring, Elise ^{[9
]}

Poznyak, Vladimir ^{[9
]}

Rekve, Dag ^{[9
]}

Oliveira Souza-Formigoni, Maria Lucia ^{[6
]}

机构：

[1] Univ Zurich, Swiss Res Inst Publ Hlth & Addict ISGF, Konradstr 32, CH-8031 Zurich, Switzerland

[2] Ramon Fuente Muniz, Natl Inst Psychiat, Mexico City, DF, Mexico

[3] Ramon Fuente Muniz, Natl Inst Psychiat, Dept Social Sci Hlth, Mexico City, DF, Mexico

[4] All India Inst Med Sci, Natl Drug Dependence Treatment Ctr, New Delhi, India

[5] All India Inst Med Sci, Dept Psychiat, New Delhi, India

[6] Univ Fed Sao Paulo, Dept Psicobiol, Escola Paulista Med, Sao Paulo, Brazil

[7] Belarusian Psychiat Assoc, Informat & Training Ctr, Minsk, BELARUS

[8] Republican Res & Practice Ctr Mental Hlth, Minsk, BELARUS

[9] WHO Dept Mental Hlth & Subst Abuse Geneva, Geneva, Switzerland

来源：

ADDICTION | 2018年 / 113卷 / 02期

关键词：

Alcohol; internet; middle-income countries; public health; self-help; World Health Organization;

D O I：

10.1111/add.14034

中图分类号：

R194 [卫生标准、卫生检查、医药管理];

学科分类号：

摘要：

Background and aimsGiven the scarcity of alcohol prevention and alcohol use disorder treatments in many low and middle-income countries, the World Health Organization launched an e-health portal on alcohol and health that includes a Web-based self-help program. This paper presents the protocol for a multicentre randomized controlled trial (RCT) to test the efficacy of the internet-based self-help intervention to reduce alcohol use. DesignTwo-arm randomized controlled trial (RCT) with follow-up 6 months after randomization. SettingCommunity samples in middle-income countries. ParticipantsPeople aged 18+, with Alcohol Use Disorders Identification Test (AUDIT) scores of 8+ indicating hazardous alcohol consumption. Intervention and comparatorOffer of an internet-based self-help intervention, Alcohol e-Health', compared with a waiting list' control group. The intervention, adapted from a previous program with evidence of effectiveness in a high-income country, consists of modules to reduce or entirely stop drinking. MeasurementsThe primary outcome measure is change in the Alcohol Use Disorders Identification Test (AUDIT) score assessed at 6-month follow-up. Secondary outcomes include self-reported the numbers of standard drinks and alcohol-free days in a typical week during the past 6 months, and cessation of harmful or hazardous drinking (AUDIT < 8). AnalysisData analysis will be by intention-to-treat, using analysis of covariance to test if program participants will experience a greater reduction in their AUDIT score than controls at follow-up. Secondary outcomes will be analysed by (generalized) linear mixed models. Complier average causal effect and baseline observations carried forward will be used in sensitivity analyses. CommentsIf the Alcohol e-Health program is found to be effective, the potential public health impact of its expansion into countries with underdeveloped alcohol prevention and alcohol use disorder treatment systems world-wide is considerable.

引用

页码：346 / 352

页数：7

共 20 条

[1]

Whiteford H.A., Degenhardt L., Rehm J., Baxter A.J., Ferrari A.J., Erskine H.E., Et al., Global burden of disease attributable to mental and substance use disorders: findings from the global burden of disease study 2010, Lancet, 382, pp. 1575-1586, (2013)

[2]

Global Status Report on Alcohol and Health 2014, (2014)

[3]

Dedert E.A., McDuffie J.R., Stein R., McNiel J.M., Kosinski A.S., Freiermuth C.E., Et al., Electronic interventions for alcohol misuse and alcohol use disorders: a systematic review, Ann Intern Med, 163, pp. 205-214, (2015)

[4]

Riper H., Blankers M., Hadiwijaya H., Cunningham J., Clarke S., Wiers R., Et al., Effectiveness of guided and unguided low-intensity internet interventions for adult alcohol misuse: a meta-analysis, PLOS ONE, 9, (2014)

[5]

Sundstrom C., Blankers M., Khadjesari Z., Computer-based interventions for problematic alcohol use: a review of systematic reviews, Int J Behav Med, 24, pp. 646-658, (2016)

[6]

Riper H., Spek V., Boon B., Conijn B., Kramer J., Martin-Abello K., Et al., Effectiveness of E-self-help interventions for curbing adult problem drinking: a meta-analysis, J Med Internet Res, 13, (2011)

[7]

Schaub M.P., Blankers M., Lehr D., Boss L., Riper H., Dekker J., Et al., Efficacy of an internet-based self-help intervention to reduce co-occurring alcohol misuse and depression symptoms in adults: study protocol of a three-arm randomised controlled trial, BMJ Open, 6, (2016)

[8]

Smit F., Lokkerbol J., Riper H., Majo M.C., Boon B., Blankers M., Modeling the cost-effectiveness of health care systems for alcohol use disorders: how implementation of eHealth interventions improves cost-effectiveness, J Med Internet Res, 13, (2011)

[9]

Global Strategy to Reduce Harmful Use of Alcohol, (2010)

[10]

Riper H., Kramer J., Smit F., Conijn B., Schippers G., Cuijpers P., Web-based self-help for problem drinkers: a pragmatic randomized trial, Addiction, 103, pp. 218-227, (2008)

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