Desensitization to drugs in children

被引：5

作者：

Ensina, Luis Felipe ^{[1
]}

Rocha Felix, Mara Morelo ^{[2
]}

da Cunha, Fernanda Sales ^{[2
]}

Caubet, Jean-Christoph ^{[3
]}

机构：

[1] Fed Univ Sao Paulo EPM UNIFESP, Dept Pediat, Sao Paulo, Brazil

[2] Univ Fed Estado Rio de Janeiro, Dept Gen Med, Rio De Janeiro, Brazil

[3] Geneva Univ Hosp, Dept Child & Adolescent, Geneva, Switzerland

来源：

ALLERGOLOGIA ET IMMUNOPATHOLOGIA | 2022年 / 50卷 / 02期

关键词：

adolescent; children; desensitization; drug allergy; drug hypersensitivity; pediatric; TRIMETHOPRIM-SULFAMETHOXAZOLE; RAPID DESENSITIZATION; HYPERSENSITIVITY REACTIONS; MONOCLONAL-ANTIBODIES; GENERAL-CONSIDERATIONS; ORAL DESENSITIZATION; RISK STRATIFICATION; INDUCED ANAPHYLAXIS; CHEMOTHERAPY; IGE;

D O I：

10.15586/aei.v50i2.539

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

Better knowledge and understanding about drug desensitization is required in the pediatric population, since there is little literature available about it and the most pediatric desensitization protocols have been adapted from adult instructions. Aiming to soften this issue and foster the future studies, this article presents a recent review about mechanisms of desensitization, diagnostic tools, and up to date management of drug hypersensitivity reactions in children. Bringing up an overview of pediatric hypersensitivity reactions to chemotherapy, biologic agents, antibiotics, nonsteroidal anti-inflammatory drugs, and vaccines. (C) 2022 Codon Publications. Published by Codon Publications.

引用

页码：48 / 57

页数：10

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