Ultrasound-induced temperature increase in guinea-pig fetal brain in utero:: Third-trimester gestation

被引：61
作者：
Horder, MM
Barnett, SB
Vella, GJ
Edwards, MJ
Wood, AKW
机构：
[1] CSIRO, Telecommun & Ind Phys, Acoust & Ultrason Discipline, Lindfield, NSW 2070, Australia
[2] Univ Sydney, Dept Vet Clin Sci, Sydney, NSW 2006, Australia
[3] Univ Sydney, Fac Hlth Sci, Sydney, NSW 2006, Australia
来源：
ULTRASOUND IN MEDICINE AND BIOLOGY | 1998年 / 24卷 / 09期
基金：
英国医学研究理事会;
关键词：
pulsed ultrasound; temperature; biological effects; fetus; hyperthermia; ultrasound safety;
D O I：
10.1016/S0301-5629(98)00090-8
中图分类号：
O42 [声学];
学科分类号：
070206 ; 082403 ;
摘要：
Temperature increase was measured at various depths in the brain of living fetal guinea pigs during in utero exposure to unscanned pulsed ultrasound at I-SPTA 2.8 W/cm(2), Mean temperature increases of 4.9 degrees C close to parietal bone and 1.2 degrees C in the midbrain were recorded after 2-min exposures. When exposures were repeated on the same sites in each fetus after death, the corresponding mean temperature increases were 4.9 degrees C and 1.3 degrees C, respectively. Cerebral blood perfusion had little cooling effect on ultrasound-induced heating in the guinea pig fetus of 57-61 days gestational age. (C) 1998 World Federation for Ultrasound in Medicine & Biology.
引用
收藏
页码：1501 / 1510
页数：10
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