Fiber intake and health in people with chronic kidney disease

被引:47
作者
Su, Guobin [1 ,2 ,3 ,4 ]
Qin, Xindong [2 ]
Yang, Changyuan [2 ]
Sabatino, Alice [5 ]
Kelly, Jaimon T. [6 ,7 ]
Avesani, Carla Maria [8 ,9 ]
Carrero, Juan Jesus [3 ]
机构
[1] Southern Med Univ, State Key Lab Organ Failure Res, Dept Nephrol,Natl Clin Res Ctr Kidney Dis, Nanfang Hosp,Guangdong Prov Clin Res Ctr Kidney D, Guangzhou, Peoples R China
[2] Guangzhou Univ Chinese Med, Guangdong Prov Hosp Chinese Med, Affiliated Hosp 2, Dept Nephrol,Clin Coll 2, Guangzhou, Peoples R China
[3] Karolinska Inst, Dept Med Epidemiol & Biostat, Stockholm, Sweden
[4] Karolinska Inst, Dept Global Publ Hlth Hlth Syst & Policy, Stockholm, Sweden
[5] Parma Univ Hosp, Dept Nephrol, Parma, Italy
[6] Univ Queensland, Ctr Online Hlth, Brisbane, Qld, Australia
[7] Univ Queensland, Ctr Hlth Serv Res, Brisbane, Qld, Australia
[8] Karolinska Inst, Dept Clin Sci Intervent & Technol, Stockholm, Sweden
[9] Karolinska Univ Hosp, Med Unit Clin Nutr, Stockholm, Sweden
基金
瑞典研究理事会; 中国博士后科学基金;
关键词
cardiovascular disease; chronic kidney disease; fiber; microbiota; mortality; prebiotics; INTERNATIONAL SCIENTIFIC ASSOCIATION; CHAIN FATTY-ACIDS; DIETARY FIBER; HEMODIALYSIS-PATIENTS; CARDIOVASCULAR EVENTS; POTASSIUM EXCRETION; CONSENSUS STATEMENT; PERITONEAL-DIALYSIS; ELDERLY-PATIENTS; RISK-FACTORS;
D O I
10.1093/ckj/sfab169
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Emerging evidence suggests that diet, particularly one that is rich in dietary fiber, may prevent the progression of chronic kidney disease (CKD) and its associated complications in people with established CKD. This narrative review summarizes the current evidence and discusses the opportunities for increasing fiber intake in people with CKD to improve health and reduce disease complications. A higher consumption of fiber exerts multiple health benefits, such as increasing stool output, promoting the growth of beneficial microbiota, improving the gut barrier and decreasing inflammation, as well decreasing uremic toxin production. Despite this, the majority of people with CKD consume less than the recommended dietary fiber intake, which may be due in part to the competing dietary potassium concern. Based on existing evidence, we see benefits from adopting a higher intake of fiber-rich food, and recommend cooperation with the dietitian to ensure an adequate diet plan. We also identify knowledge gaps for future research and suggest means to improve patient adherence to a high-fiber diet.
引用
收藏
页码:213 / 225
页数:13
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