Anti-inflammatory compounds of plant origin.: Part I.: Action on arachidonic acid pathway, nitric oxide and nuclear factor κB (NF-κB)

被引:0
作者
Calixto, JB
Otuki, MF
Santos, ARS
机构
[1] Univ Fed Santa Catarina, Dept Pharmacol, CCB, BR-88015420 Florianopolis, SC, Brazil
[2] Univ Fed Santa Catarina, Dept Physiol Sci, CCB, BR-88015420 Florianopolis, SC, Brazil
关键词
medicinal plants; plant constituents; inflammation;
D O I
暂无
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Over the last 10 years, a significant body of evidence has emerged indicating that chemically diverse classes of naturally-occurring substances derived from higher plants are of potential interest for therapeutic interventions in several inflammatory diseases. Part I of this review article focuses on our current knowledge of the mechanisms by which a large range of plant-derived constituents interfere with three relevant targets involved in the inflammatory process, namely arachidonic acid metabolite pathways, nitric oxide and NF-kappaB, and discusses their potential therapeutic use in the management of relevant inflammatory diseases.
引用
收藏
页码:973 / 983
页数:11
相关论文
共 50 条
[31]   Anti-Inflammatory Effect of Garcinol Extracted from Garcinia dulcis via Modulating NF-κB Signaling Pathway [J].
Chantree, Pathanin ;
Martviset, Pongsakorn ;
Thongsepee, Nattaya ;
Sangpairoj, Kant ;
Sornchuer, Phornphan .
NUTRIENTS, 2023, 15 (03)
[32]   Anti-inflammatory effects of galangin on lipopolysaccharide-activated macrophages via ERK and NF-κB pathway regulation [J].
Jung, Yun Chan ;
Kim, Mi Eun ;
Yoon, Ju Hwa ;
Park, Pu Reum ;
Youn, Hwa-Young ;
Lee, Hee-Woo ;
Lee, Jun Sik .
IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY, 2014, 36 (06) :426-432
[33]   Astaxanthin inhibits nitric oxide production and inflammatory gene expression by suppressing IκB kinase-dependent NF-κB activation [J].
Lee, SJ ;
Bai, SK ;
Lee, KS ;
Namkoong, S ;
Na, HJ ;
Ha, KS ;
Han, JA ;
Yim, SV ;
Chang, K ;
Kwon, YG ;
Lee, SK ;
Kim, YM .
MOLECULES AND CELLS, 2003, 16 (01) :97-105
[34]   Astragaloside IV exerts anti-inflammatory role in endometriosis by downregulating TLR4/NF-κB pathway [J].
Zhang, Yongping ;
Huang, Ouping ;
Zhang, Wei ;
Liu, Luxin ;
Xu, Caiwei .
TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH, 2019, 18 (03) :539-545
[35]   Anti-inflammatory effect of Barringtonia angusta methanol extract is mediated by targeting of Src in the NF-κB signalling pathway [J].
Jo, Minkyeong ;
Lee, Jongsung ;
Kim, Han Gyung ;
Kim, Jin Kyeong ;
Kim, Haeyeop ;
Shin, Kon Kuk ;
Bach, Tran The ;
Eum, Sang Mi ;
Lee, Jong Sub ;
Choung, Eui Su ;
Yang, Yoonyong ;
Kim, Kyung-Hee ;
Sung, Gi-Ho ;
Yoo, Byong Chul ;
Cho, Jae Youl .
PHARMACEUTICAL BIOLOGY, 2021, 59 (01) :799-810
[36]   Bullatine A exerts anti-inflammatory effects by inhibiting the ROS/JNK/NF-κB pathway and attenuating systemic inflammatory responses in mice [J].
Liu, Shuhan ;
Che, Na ;
Ou, Wen ;
Yan, Meichen ;
Liao, Yajin ;
Cheng, Yong .
PHARMACEUTICAL BIOLOGY, 2022, 60 (01) :1840-1849
[37]   A novel inflammatory signaling pathway in patients with slow coronary flow: NF-κB/IL-1β/nitric oxide [J].
Roshanravan, Neda ;
Shabestari, Alireza Namazi ;
Alamdari, Naimeh Mesri ;
Ostadrahimi, Alireza ;
Separham, Ahmad ;
Parvizi, Rezayat ;
Jafarabadi, Mohammad Asghari ;
Ghodrat, Mahshid ;
Akbarzadeh, Moloud ;
Naemi, Mohammad ;
Ghazi, Mahdiyeh Khabbaz Koche ;
Hadi, Amir ;
Ghaffari, Samad .
CYTOKINE, 2021, 143
[38]   NF-κB as a target for anti-inflammatory gene therapy: suppression of inflammatory responses in monocytic and stromal cells by stable gene transfer of IκBα cDNA [J].
SS Makarov ;
WN Johnston ;
JC Olsen ;
JM Watson ;
K Mondal ;
C Rinehart ;
JS Haskill .
Gene Therapy, 1997, 4 :846-852
[39]   Anti-inflammatory and anti-arthritic properties of naringenin via attenuation of NF-κB and activation of the heme oxygenase (HO)-1/related factor 2 pathway [J].
Fan, Rong ;
Pan, Tong ;
Zhu, An-Li ;
Zhang, Mei-Hong .
PHARMACOLOGICAL REPORTS, 2017, 69 (05) :1021-1029
[40]   Anti-inflammatory effects of a Chinese herbal medicine in atherosclerosis via estrogen receptor β mediating nitric oxide production and NF-κB suppression in endothelial cells [J].
L Wang ;
X-M Qiu ;
Q Hao ;
D-J Li .
Cell Death & Disease, 2013, 4 :e551-e551