Anti-inflammatory compounds of plant origin.: Part I.: Action on arachidonic acid pathway, nitric oxide and nuclear factor κB (NF-κB)

被引:0
作者
Calixto, JB
Otuki, MF
Santos, ARS
机构
[1] Univ Fed Santa Catarina, Dept Pharmacol, CCB, BR-88015420 Florianopolis, SC, Brazil
[2] Univ Fed Santa Catarina, Dept Physiol Sci, CCB, BR-88015420 Florianopolis, SC, Brazil
关键词
medicinal plants; plant constituents; inflammation;
D O I
暂无
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Over the last 10 years, a significant body of evidence has emerged indicating that chemically diverse classes of naturally-occurring substances derived from higher plants are of potential interest for therapeutic interventions in several inflammatory diseases. Part I of this review article focuses on our current knowledge of the mechanisms by which a large range of plant-derived constituents interfere with three relevant targets involved in the inflammatory process, namely arachidonic acid metabolite pathways, nitric oxide and NF-kappaB, and discusses their potential therapeutic use in the management of relevant inflammatory diseases.
引用
收藏
页码:973 / 983
页数:11
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