Anti-inflammatory compounds of plant origin.: Part I.: Action on arachidonic acid pathway, nitric oxide and nuclear factor κB (NF-κB)

被引:0
|
作者
Calixto, JB
Otuki, MF
Santos, ARS
机构
[1] Univ Fed Santa Catarina, Dept Pharmacol, CCB, BR-88015420 Florianopolis, SC, Brazil
[2] Univ Fed Santa Catarina, Dept Physiol Sci, CCB, BR-88015420 Florianopolis, SC, Brazil
关键词
medicinal plants; plant constituents; inflammation;
D O I
暂无
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Over the last 10 years, a significant body of evidence has emerged indicating that chemically diverse classes of naturally-occurring substances derived from higher plants are of potential interest for therapeutic interventions in several inflammatory diseases. Part I of this review article focuses on our current knowledge of the mechanisms by which a large range of plant-derived constituents interfere with three relevant targets involved in the inflammatory process, namely arachidonic acid metabolite pathways, nitric oxide and NF-kappaB, and discusses their potential therapeutic use in the management of relevant inflammatory diseases.
引用
收藏
页码:973 / 983
页数:11
相关论文
共 50 条
  • [1] Anti-inflammatory action of physalin A by blocking the activation of NF-κB signaling pathway
    Wang, Liying
    Gu, Jinpo
    Zong, Mingyue
    Zhang, Qingran
    Li, Huixiang
    Li, Danna
    Mou, Xiaofeng
    Liu, Pan
    Liu, Yanan
    Qiu, Feng
    Zhao, Feng
    JOURNAL OF ETHNOPHARMACOLOGY, 2021, 267
  • [2] Extraction and structural profiling of polysaccharides from Rehmannia glutinosa and anti-inflammatory action via the NF-κB/IκBα pathway
    Xie, Meixia
    Cai, Jiale
    Zhong, Xiaoting
    Liang, Jiayin
    Liang, Shengwang
    Xian, Minghua
    Yan, Chunyan
    Wang, Shumei
    INDUSTRIAL CROPS AND PRODUCTS, 2024, 208
  • [3] Study of Anti-Inflammatory Action of Aurothiomalate, an Inhibitor of NF-κB
    Belsky, Yu. P.
    Ivanova, A. N.
    Danilets, M. G.
    Belska, N. V.
    Ligatcheva, A. A.
    Uchasova, E. G.
    Reikhart, D. V.
    BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE, 2011, 151 (02) : 190 - 193
  • [4] Study of Anti-Inflammatory Action of Aurothiomalate, an Inhibitor of NF-κB
    Yu. P. Belsky
    A. N. Ivanova
    M. G. Danilets
    N. V. Belska
    A. A. Ligatcheva
    E. G. Uchasova
    D. V. Reikhart
    Bulletin of Experimental Biology and Medicine, 2011, 151
  • [5] In vitro anti-inflammatory activity of terpenes via suppression of superoxide and nitric oxide generation and the NF-κB signalling pathway
    Franciane Martins Marques
    Mariana Moreira Figueira
    Elisângela Flávia Pimentel Schmitt
    Tamara P. Kondratyuk
    Denise Coutinho Endringer
    Rodrigo Scherer
    Marcio Fronza
    Inflammopharmacology, 2019, 27 : 281 - 289
  • [6] β-Adrenergic agonists exert their "anti-inflammatory" effects in monocytic cells through the IκB/NF-κB pathway
    Farmer, P
    Pugin, J
    AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 2000, 279 (04) : L675 - L682
  • [7] Insulin Exerts Anti-Inflammatory Effects through Reduction of IKK/IκB/NF-κB Pathway Activation
    Mittestainer, Francine Cappa
    Aranha Pereira Camacho, Angelica Costa
    Silva Calisto, Kelly Lima
    Carvalho, Bruno De Melo
    De Oliveira, Alexandre Gabarra
    Guadagnini, Dioze
    Abdalla Saad, Mario Jose
    DIABETES, 2011, 60 : A426 - A426
  • [8] Anti-inflammatory and analgesic activities of indigo through regulating the IKKβ/IκB/NF-κB pathway in mice
    Liu, Ning
    Zhang, Guo-Xin
    Niu, Ya-Ting
    Wang, Qing
    Zheng, Jie
    Yang, Jia-Mei
    Sun, Tao
    Niu, Jian-Guo
    Yu, Jian-Qiang
    FOOD & FUNCTION, 2020, 11 (10) : 8537 - 8546
  • [9] Peperomins as anti-inflammatory agents that inhibit the NF-κB signaling pathway
    Tsutsui, Chieko
    Yamada, Yuriko
    Ando, Masayoshi
    Toyama, Daisuke
    Wu, Jian-lin
    Wang, Liyan
    Taketani, Shigeru
    Kataoka, Takao
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2009, 19 (15) : 4084 - 4087
  • [10] Anti-inflammatory effect of prunetin via the suppression of NF-κB pathway
    Yang, Gabsik
    Ham, Inhye
    Choi, Ho-Young
    FOOD AND CHEMICAL TOXICOLOGY, 2013, 58 : 124 - 132