Are antibodies directed against amyloid- (A) oligomers the last call for the A hypothesis of Alzheimer's disease?

被引：56

作者：

Panza, Francesco ^{[1
,2
,3
]}

Lozupone, Madia ^{[1
]}

Dibello, Vittorio ^{[4
]}

Greco, Antonio ^{[3
]}

Daniele, Antonio ^{[5
,6
]}

Seripa, Davide ^{[3
]}

Logroscino, Giancarlo ^{[1
,2
]}

Imbimbo, Bruno P. ^{[7
]}

机构：

[1] Univ Bari Aldo Moro, Dept Basic Med Neurosci & Sense Organs, Neurodegenerat Dis Unit, Bari, Italy

[2] Univ Bari Aldo Moro, Pia Fdn Cardinale G Panico, Ctr Neurodegenerat Dis & AgingBrain, Dept Clin Res Neurol, Lecce, Italy

[3] Fdn IRCCS Casa Sollievo Sofferenza, Geriat Unit, Foggia, Italy

[4] Univ Bari Aldo Moro, Sect Dent, Interdisciplinary Dept Med DIM, Bari, Italy

[5] Univ Cattolica Sacro Cuore, Inst Neurol, Rome, Italy

[6] Fdn Policlin Univ A Gemelli IRCCS, Rome, Italy

[7] Chiesi Farmaceut, Dept Researchand Dev, Parma, Italy

来源：

IMMUNOTHERAPY | 2019年 / 11卷 / 01期

关键词：

aducanumab; Alzheimer's disease; BAN2401; dementia; MCI; monoclonal antibodies; passive immunotherapy; prodromal Alzheimer's disease; A-BETA; TRIAL;

D O I：

10.2217/imt-2018-0119

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

[No abstract available]

引用

页码：3 / 6

页数：4

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