Extracellular vesicles in the oligodendrocyte microenvironment

被引：27

作者：

Kraemer-Albers, Eva-Maria ^{[1
]}

机构：

[1] Johannes Gutenberg Univ Mainz, Inst Dev Biol & Neurobiol, Biol Extracellular Vesicles Grp, Cellular Neurobiol, Hanns Dieter Husch Weg 15, D-55128 Mainz, Germany

来源：

NEUROSCIENCE LETTERS | 2020年 / 725卷

关键词：

Oligodendrocytes; Myelination; Neuron-glia interaction; Extracellular vesicles; Exosomes; Microenvironment; Tissue homeostasis; TROPHIC SUPPORT; EXOSOMES; CELLS; MACROPINOCYTOSIS; COMMUNICATION; MYELINATION; PROTEINS;

D O I：

10.1016/j.neulet.2020.134915

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Extracellular vesicles (EVs) recently took centre stage as mediators of cellular crosstalk modulating the tissue microenvironment. Released by all types of neural cells, EVs may execute a broad spectrum of functions ranging from maintenance of neuronal homeostasis and regulation of neural plasticity to the spread of neurodegenerative agents. Myelinating oligodendrocytes and axons form a highly specialized functional entity that depends on intimate interactions within the oligodendrocyte-neuron niche. EVs released by oligodendrocytes are internalized by neurons in response to neuronal signals and exhibit neuroprotective properties but also may influence other cells present in the microenvironment. Here we discuss the role of EVs released by oligodendrocytes in regulating development, homeostatic maintenance and regeneration within the oligodendrocyte niche.

引用

页数：5

共 45 条

[1] Retrovirus-like Gag Protein Arc1 Binds RNA and Traffics across Synaptic Boutons [J].

Ashley, James ;

Cordy, Benjamin ;

Lucia, Diandra ;

Fradkin, Lee G. ;

Budnik, Vivian ;

Thomson, Travis .

CELL, 2018, 172 (1-2) :262-+

[2] Inhibition of Myelin Membrane Sheath Formation by Oligodendrocyte-derived Exosome-like Vesicles [J].

Bakhti, Mostafa ;

Winter, Christine ;

Simons, Mikael .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2011, 286 (01) :787-796

[3] Role of Microvesicles in the Spread of Herpes Simplex Virus 1 in Oligodendrocytic Cells [J].

Bello-Morales, Raquel ;

Praena, Beatriz ;

de la Nuez, Carmen ;

Teresa Rejas, Maria ;

Guerra, Milagros ;

Galan-Ganga, Marcos ;

Izquierdo, Manuel ;

Calvo, Victor ;

Krummenacher, Claude ;

Antonio Lopez-Guerrero, Jose .

JOURNAL OF VIROLOGY, 2018, 92 (10)

[4] Extracellular vesicles round off communication in the nervous system [J].

Budnik, Vivian ;

Ruiz-Canada, Catalina ;

Wendler, Franz .

NATURE REVIEWS NEUROSCIENCE, 2016, 17 (03) :160-172

[5] Exosomes secreted by cortical neurons upon glutamatergic synapse activation specifically interact with neurons [J].

Chivet, Mathilde ;

Javalet, Charlotte ;

Laulagnier, Karine ;

Blot, Beatrice ;

Hemming, Fiona J. ;

Sadoul, Remy .

JOURNAL OF EXTRACELLULAR VESICLES, 2014, 3 (01)

[6] Cytokines Stimulate the Release of Microvesicles from Myeloid Cells Independently from the P2X7 Receptor/Acid Sphingomyelinase Pathway [J].

Colombo, Federico ;

Bastoni, Mattia ;

Nigro, Annamaria ;

Podini, Paola ;

Finardi, Annamaria ;

Casella, Giacomo ;

Ramesh, Menon ;

Farina, Cinthia ;

Verderio, Claudia ;

Furlan, Roberto .

FRONTIERS IN IMMUNOLOGY, 2018, 9

[7] ATP Modifies the Proteome of Extracellular Vesicles Released by Microglia and Influences Their Action on Astrocytes [J].

Drago, Francesco ;

Lombardi, Marta ;

Prada, Ilaria ;

Gabrielli, Martina ;

Joshi, Pooja ;

Cojoc, Dan ;

Franck, Julien ;

Fournier, Isabelle ;

Vizioli, Jacopo ;

Verderio, Claudia .

FRONTIERS IN PHARMACOLOGY, 2017, 8

[8] The crosstalk between hematopoietic stem cells and their niches [J].

Durand, Charles ;

Charbord, Pierre ;

Jaffredo, Thierry .

CURRENT OPINION IN HEMATOLOGY, 2018, 25 (04) :285-289

[9] Exosomes as Novel Regulators of Adult Neurogenic Niches [J].

Federico Batiz, Luis ;

Castro, Maite A. ;

Burgos, Patricia V. ;

Velasquez, Zahady D. ;

Munoz, Rosa I. ;

Lafourcade, Carlos A. ;

Troncoso-Escudero, Paulina ;

Wyneken, Ursula .

FRONTIERS IN CELLULAR NEUROSCIENCE, 2016, 9

[10] Selective transfer of exosomes from oligodendrocytes to microglia by macropinocytosis [J].

Fitzner, Dirk ;

Schnaars, Mareike ;

van Rossum, Denise ;

Krishnamoorthy, Gurumoorthy ;

Dibaj, Payam ;

Bakhti, Mostafa ;

Regen, Tommy ;

Hanisch, Uwe-Karsten ;

Simons, Mikael .

JOURNAL OF CELL SCIENCE, 2011, 124 (03) :447-458

← 1 2 3 4 5 →