Larrea tridentata and its Biological Activities

被引:7
作者
Reyes-Melo, Karen Y. [1 ]
Galvan-Rodrigo, Adrian A. [1 ]
Martinez-Olivo, Isai E. [1 ]
Nunez-Mojica, Guillermo [1 ]
Avalos-Alanis, Francisco G. [1 ]
Garcia, Abraham [1 ]
del Rayo Camacho-Corona, Maria [1 ]
机构
[1] Univ Autonoma Nuevo Leon, Fac Ciencias Quim, San Nicolas De Los Garza 66455, Nuevo Leon, Mexico
关键词
Larrea tridentata; Lignans; Flavonoids; Antibacterial; Antiviral; Anticancer; Antioxidant; NORDIHYDROGUAIARETIC ACID; POTENTIAL MECHANISM; CREOSOTE BUSH; PLANT LIGNAN; EXTRACTS; MEXICAN; TUBERCULOSIS; INHIBITION; INGESTION; HEPATITIS;
D O I
10.2174/1568026621666210727170908
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Background: Larrea tridentata is a dominant shrub in the deserts of North America and is recognized for its various traditional uses. More than 50 traditional uses have been recorded. Re-garding its chemical composition, the products of the mevalonate, shikimate, and malonate path-ways are predominant. L. tridentata has nordihydroguaiaretic acid (NDGA), one of its most studied secondary metabolites that exhibited remarkable different biological activities: sequestration of re-active oxygen species, inhibition of lipoxygenases (LOX) and activation of the endogenous antioxi-dant response mediated by nuclear factor erythroid 2-related factor 2 (NRF2). Objective and Methods: This review seeks to draw attention to metabolites other than NDGA and which also contribute to the various biological activities of L. tridentata. Therefore, the present re-view includes those reports focused on the pharmacological properties of the organic extracts of L. tridentata and its natural products with promising values. Results and Conclusion: Among the most promising and widely reported metabolites from L. tri-dentata, are: 3'-demethoxy-6-O-demethylisoguaiacin, 3'-O-methyldihydroguaiaretic acid, meso-di-hydroguaiaretic acid, and tetra-O-methylnordihydroguaiaretic acid. These have been reported to ex-hibit antibacterial, antiprotozoal, anthelmintic, antifungal, antiviral, anticancer, and antioxidant ac-tivities.
引用
收藏
页码:2352 / 2364
页数:13
相关论文
共 57 条
  • [1] Antioxidant lignans from Larrea tridentata
    Abou-Gazar, H
    Bedir, E
    Takamatsu, S
    Ferreira, D
    Khan, IA
    [J]. PHYTOCHEMISTRY, 2004, 65 (17) : 2499 - 2505
  • [2] CHOLESTATIC HEPATITIS AFTER INGESTION OF CHAPARRAL LEAF - CONFIRMATION BY ENDOSCOPIC RETROGRADE CHOLANGIOPANCREATOGRAPHY AND LIVER-BIOPSY
    ALDERMAN, S
    KAILAS, S
    GOLDFARB, S
    SINGARAM, C
    MALONE, DG
    [J]. JOURNAL OF CLINICAL GASTROENTEROLOGY, 1994, 19 (03) : 242 - 247
  • [3] A plant lignan, 3′-O-methyl-nordihydroguaiaretic acid, suppresses papillomavirus E6 protein function, stabilizes p53 protein, and induces apoptosis in cervical tumor cells
    Allen, Kristi L.
    Tschantz, Deidra R.
    Awad, Keytam S.
    Lynch, William P.
    DeLucia, Angelo L.
    [J]. MOLECULAR CARCINOGENESIS, 2007, 46 (07) : 564 - 575
  • [4] [Anonymous], 2001, BIOSCI BIOTECH BIOCH, V65, P996, DOI [10.1271/bbb.65.996, DOI 10.1271/BBB.65.996]
  • [5] Larrea tridentata (Creosote bush), an abundant plant of Mexican and US-American deserts and its metabolite nordihydroguaiaretic acid
    Arteaga, S
    Andrade-Cetto, A
    Cárdenas, R
    [J]. JOURNAL OF ETHNOPHARMACOLOGY, 2005, 98 (03) : 231 - 239
  • [6] Larrea tridentata: A novel source for antiparasitic agents active against Entamoeba histolytica, Giardia lamblia and Naegleria fowleri
    Bashyal, Bharat
    Li, Linfeng
    Bains, Trpta
    Debnath, Anjan
    LaBarbera, Daniel V.
    [J]. PLOS NEGLECTED TROPICAL DISEASES, 2017, 11 (08):
  • [7] BATCHELOR WB, 1995, AM J GASTROENTEROL, V90, P831
  • [8] Argentinean Andean propolis associated with the medicinal plant Larrea nitida Cav. (Zygophyllaceae). HPLC-MS and GC-MS characterization and antifungal activity
    Belen Agueero, Maria
    Svetaz, Laura
    Sanchez, Marianela
    Luna, Lorena
    Lima, Beatriz
    Liza Lopez, Maria
    Zacchino, Susana
    Palermo, Jorge
    Wunderlin, Daniel
    Egly Feresin, Gabriela
    Tapia, Alejandro
    [J]. FOOD AND CHEMICAL TOXICOLOGY, 2011, 49 (09) : 1970 - 1978
  • [9] The bioactivity of plant extracts against representative bacterial pathogens of the lower respiratory tract
    Bocanegra-García V.
    Del Rayo Camacho-Corona M.
    Ramírez-Cabrera M.
    Rivera G.
    Garza-Gonzlez E.
    [J]. BMC Research Notes, 2 (1)
  • [10] Activity against drug resistant-tuberculosis strains of plants used in Mexican traditional medicine to treat tuberculosis and other respiratory diseases
    Camacho-Corona, Maria del Rayo
    Ramirez-Cabrera, Monica A.
    Gonzalez-Santiago, Omar
    Garza-Gonzalez, Elvira
    Palacios, Isidoro de Paz
    Luna-Herrera, Julieta
    [J]. PHYTOTHERAPY RESEARCH, 2008, 22 (01) : 82 - 85