Ischemia-modified albumin and cardiovascular risk markers in polycystic ovary syndrome with or without insulin resistance

被引：45

作者：

Caglar, Gamze S. ^{[1
]}

Oztas, Efser ^{[1
]}

Karadag, Demet ^{[2
]}

Pabuccu, Recai ^{[1
]}

Demirtas, Selda ^{[3
]}

机构：

[1] Univ Ufuk, Fac Med, Dept Obstet & Gynecol, TR-06530 Ankara, Turkey

[2] Univ Ufuk, Fac Med, Dept Radiol, TR-06530 Ankara, Turkey

[3] Univ Ufuk, Fac Med, Dept Biochem, TR-06530 Ankara, Turkey

来源：

FERTILITY AND STERILITY | 2011年 / 95卷 / 01期

关键词：

Ovary syndrome; ischemia modified albumin; cardiovascular risk; insulin resistance; TYPE-2; DIABETES-MELLITUS; C-REACTIVE PROTEIN; MIDDLE-AGED WOMEN; ENDOTHELIAL DYSFUNCTION; CHRONIC INFLAMMATION; METABOLIC SYNDROME; ATHEROSCLEROSIS; DISEASE; PREVALENCE; OBESITY;

D O I：

10.1016/j.fertnstert.2010.06.092

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

The aim of this study was to evaluate ischemia-modified albumin levels (IMA) in polycystic ovary syndrome (PCOS) cases with and without insulin resistance and the correlation of IMA with carotid intima media thickness, homocysteine, and high-sensitivity C-reactive protein levels. Significantly higher levels of IMA in young lean PCOS cases, more relevant in insulin resistant cases, indicates chronic hypoxia and oxidative stress which might play a role in the metabolic consequences in PCOS. (Fertil Steril (R) 2011; 95:310-3. (c) 2011 by American Society for Reproductive Medicine.)

引用

页码：310 / 313

页数：4

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