Novel rearrangement of 7-(substituted aminomethyl)-6,7-dihydrooxazolo[2,3-f]purines to 7-(substituted amino)-7,8-dihydro-6H-[1,3]oxazino[2,3-f]purines

被引：3

作者：

Cegla, MT

Potaczek, J

Zylewski, M

Strekowski, L

机构：

[1] Jagiellonian Univ, Coll Med, Fac Pharm, Dept Organ Chem, PL-30688 Krakow, Poland

[2] Georgia State Univ, Dept Chem, Atlanta, GA 30302 USA

来源：

TETRAHEDRON LETTERS | 2005年 / 46卷 / 20期

关键词：

6,7-dihydrooxazolo[2,3-f]purine-2,4(1H,3H)-dione; rearrangement; 6,7-dihydro[2,3-f]purine-2,4(1H,3H)-dione;

D O I：

10.1016/j.tetlet.2005.03.111

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Oxazinopurines were obtained in high yield by the reaction of 8-bromotheophyl line with morpholinomethyl-, piperidinomethyl- or indolinomethyl-substituted oxiranes without isolation of the intermediate oxazolo[2,3-f]purine. © 2005 Elsevier Ltd. All rights reserved.

引用

页码：3561 / 3563

页数：3

共 10 条

[1]

[Anonymous], 1972, ACTA PHARM JUGOSLAV

[2] Synthesis and pharmacological evaluation of 5-dialkylaminomethyl-2-amino-2-oxazolines as H1-antagonists [J].