IL-10 overexpression predisposes to invasive aspergillosis by suppressing antifungal immunity

被引：44

作者：

Cunha, Cristina ^{[1
,2
]}

Goncalves, Samuel M. ^{[1
,2
]}

Duarte-Oliveira, Claudio ^{[1
,2
]}

Leite, Luis ^{[3
]}

Lagrou, Katrien ^{[4
,5
,6
]}

Marques, Antonio ^{[8
]}

Lupianez, Carmen B. ^{[9
,10
]}

Mesquita, Ines ^{[1
,2
]}

Gaifem, Joana ^{[1
,2
]}

Barbosa, Ana Margarida ^{[1
,2
]}

Vaz, Carlos Pinho ^{[3
]}

Branca, Rosa ^{[3
]}

Campilho, Fernando ^{[3
]}

Freitas, Fatima ^{[11
]}

Ligeiro, Dario ^{[12
]}

Lass-Floerl, Cornelia ^{[13
]}

Loffler, Jurgen ^{[14
]}

Jurado, Manuel ^{[10
]}

Saraiva, Margarida ^{[15
,16
]}

Kurzai, Oliver ^{[17
]}

Rodrigues, Fernando ^{[1
,2
]}

Castro, Antonio G. ^{[1
,2
]}

Silvestre, Ricardo ^{[1
,2
]}

Sainz, Juan ^{[9
,10
]}

Maertens, Johan A. ^{[7
]}

Torrado, Egidio ^{[1
,2
]}

Jacobsen, Ilse D. ^{[18
,19
]}

Lacerda, Joao F. ^{[20
,21
]}

Campos, Antonio, Jr. ^{[3
]}

Carvalho, Agostinho ^{[1
,2
]}

机构：

[1] Univ Minho, Sch Med, Life & Hlth Sci Res Inst ICVS, Braga, Portugal

[2] ICVS 3B, PT Govt Associate Lab, Braga, Portugal

[3] Inst Portugues Oncol Francisco Gentil, Serv Transplant Medula Ossea, Oporto, Portugal

[4] KU Leuven Univ, Dept Microbiol & Immunol, Leuven, Belgium

[5] Univ Hosp Leuven, Dept Lab Med, Leuven, Belgium

[6] Univ Hosp Leuven, Natl Reference Ctr Med Mycol, Leuven, Belgium

[7] Univ Hosp Leuven, Dept Hematol, Leuven, Belgium

[8] Hosp Braga, Serv Imunohemoterapia, Braga, Portugal

[9] Univ Granada, Andalusian Reg Gov, Pfizer,PTS, Ctr Genom & Oncol Res,GENYO,Genom Oncol Area, Granada, Spain

[10] Virgen de las Nieves Univ Hosp, Hematol Dept, Granada, Spain

[11] Inst Portugues Sangue & Transplant, Oporto, Portugal

[12] Inst Portugues Sangue & Transplant, Lisbon, Portugal

[13] Med Univ Innsbruck, Div Hyg & Med Microbiol, Innsbruck, Austria

[14] Univ Hosp Wurzburg, Dept Internal Med 2, Wurzburg, Germany

[15] Univ Porto, I3S Inst Invest Inovacao Saude, Oporto, Portugal

[16] Univ Porto, IBMC, Oporto, Portugal

[17] Friedrich Schiller Univ, Sept Res Ctr, Jena, Germany

[18] Friedrich Schiller Univ, Res Grp Microbial Immunol, Jena, Germany

[19] Leibniz Inst Nat Prod Res & Infect Biol, Hans Knoll Inst, Jena, Germany

[20] Inst Med Mol, Fac Med Lisboa, r, Lisbon, Portugal

[21] Hosp Santa Maria, Serv Hematol & Transplant Medula, s, Lisbon, Portugal

来源：

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY | 2017年 / 140卷 / 03期

关键词：

IDENTIFICATION; CLINICIAN; DISEASE; GUIDE;

D O I：

10.1016/j.jaci.2017.02.034

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

[No abstract available]

引用

页码：867 / +

页数：13

共 17 条

[1] A map of human genome variation from population-scale sequencing [J].

Altshuler, David ;

Durbin, Richard M. ;

Abecasis, Goncalo R. ;

Bentley, David R. ;

Chakravarti, Aravinda ;

Clark, Andrew G. ;

Collins, Francis S. ;

De la Vega, Francisco M. ;

Donnelly, Peter ;

Egholm, Michael ;

Flicek, Paul ;

Gabriel, Stacey B. ;

Gibbs, Richard A. ;

Knoppers, Bartha M. ;

Lander, Eric S. ;

Lehrach, Hans ;

Mardis, Elaine R. ;

McVean, Gil A. ;

Nickerson, DebbieA. ;

Peltonen, Leena ;

Schafer, Alan J. ;

Sherry, Stephen T. ;

Wang, Jun ;

Wilson, Richard K. ;

Gibbs, Richard A. ;

Deiros, David ;

Metzker, Mike ;

Muzny, Donna ;

Reid, Jeff ;

Wheeler, David ;

Wang, Jun ;

Li, Jingxiang ;

Jian, Min ;

Li, Guoqing ;

Li, Ruiqiang ;

Liang, Huiqing ;

Tian, Geng ;

Wang, Bo ;

Wang, Jian ;

Wang, Wei ;

Yang, Huanming ;

Zhang, Xiuqing ;

Zheng, Huisong ;

Lander, Eric S. ;

Altshuler, David L. ;

Ambrogio, Lauren ;

Bloom, Toby ;

Cibulskis, Kristian ;

Fennell, Tim J. ;

Gabriel, Stacey B. .

NATURE, 2010, 467 (7319) :1061-1073

[2] Human Genetic Susceptibility to Invasive Aspergillosis [J].

Cunha, Cristina ;

Aversa, Franco ;

Romani, Luigina ;

Carvalho, Agostinho .

PLOS PATHOGENS, 2013, 9 (08)

[3] Revised definitions of invasive fungal disease from the European Organization for Research and Treatment of Cancer/Invasive Fungal Infections Cooperative Group and the National Institute of Allergy and Infectious Diseases Mycoses Study Group (EORTC/MSG) Consensus Group [J].

De Pauw, Ben ;

Walsh, Thomas J. ;

Donnelly, J. Peter ;

Stevens, David A. ;

Edwards, John E. ;

Calandra, Thierry ;

Pappas, Peter G. ;

Maertens, Johan ;

Lortholary, Olivier ;

Kauffman, Carol A. ;

Denning, David W. ;

Patterson, Thomas F. ;

Maschmeyer, Georg ;

Bille, Jacques ;

Dismukes, William E. ;

Herbrecht, Raoul ;

Hope, William W. ;

Kibbler, Christopher C. ;

Kullberg, Bart Jan ;

Marr, Kieren A. ;

Munoz, Patricia ;

Odds, Frank C. ;

Perfect, John R. ;

Restrepo, Angela ;

Ruhnke, Markus ;

Segal, Brahm H. ;

Sobel, Jack D. ;

Sorrell, Tania C. ;

Viscoli, Claudio ;

Wingard, John R. ;

Zaoutis, Theoklis ;

Bennett, John E. .

CLINICAL INFECTIOUS DISEASES, 2008, 46 (12) :1813-1821

[4] Identification of patterns in biological sequences at the ALGGEN server:: PROMO and MALGEN [J].

Farré, D ;

Roset, R ;

Huerta, M ;

Adsuara, JE ;

Roselló, L ;

Albà, MM ;

Messeguer, X .

NUCLEIC ACIDS RESEARCH, 2003, 31 (13) :3651-3653

[5] A CLASS OF K-SAMPLE TESTS FOR COMPARING THE CUMULATIVE INCIDENCE OF A COMPETING RISK [J].

GRAY, RJ .

ANNALS OF STATISTICS, 1988, 16 (03) :1141-1154

[6] Report of ERS Task Force: guidelines for measurement of acellular components and standardization of BAL [J].

Haslam, PL ;

Baughman, RP .

EUROPEAN RESPIRATORY JOURNAL, 1999, 14 (02) :245-248

[7] Differential Production of Type I IFN Determines the Reciprocal Levels of IL-10 and Proinflammatory Cytokines Produced by C57BL/6 and BALB/c Macrophages [J].

Howes, Ashleigh ;

Taubert, Christina ;

Blankley, Simon ;

Spink, Natasha ;

Wu, Xuemei ;

Graham, Christine M. ;

Zhao, Jiawen ;

Saraiva, Margarida ;

Ricciardi-Castagnoli, Paola ;

Bancroft, Gregory J. ;

O'Garra, Anne .

JOURNAL OF IMMUNOLOGY, 2016, 197 (07) :2838-2853

[8] SNAP: a web-based tool for identification and annotation of proxy SNPs using HapMap [J].

Johnson, Andrew D. ;

Handsaker, Robert E. ;

Pulit, Sara L. ;

Nizzari, Marcia M. ;

O'Donnell, Christopher J. ;

de Bakker, Paul I. W. .

BIOINFORMATICS, 2008, 24 (24) :2938-2939

[9] The Septic Shock-Associated IL-10-1082 A > G Polymorphism Mediates Allele-Specific Transcription via Poly(ADP-Ribose) Polymerase 1 in Macrophages Engulfing Apoptotic Cells [J].

Kang, Xiaoyan ;

Kim, Ha-Jeong ;

Ramirez, Michelle ;

Salameh, Sarah ;

Ma, Xiaojing .

JOURNAL OF IMMUNOLOGY, 2010, 184 (07) :3718-3724

[10] Sp1 binds to the G allele of the-1087 polymorphism in the IL-10 promoter and promotes IL-10 mRNA transcription and protein production [J].

Larsson, L. ;

Rymo, L. ;

Berglundh, T. .

GENES AND IMMUNITY, 2010, 11 (02) :181-187

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