First total synthesis of panaxytriol, a potent antitumor agent isolated from Panax ginseng

被引：0
|
作者：
Lu, W [1 ]
Zheng, GR [1 ]
Cai, JC [1 ]
机构：
[1] Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai 200031, Peoples R China
来源：
SYNLETT | 1998年 / 07期
关键词：
panaxytriol; antitumor agent; Ginseng; total synthesis; stereostructure;
D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Panaxytriol 1, a potent antitumor agent isolated from Panax ginseng, was first synthesized, and its stereostructure was confirmed to be (3R, 9R, 10R)-heptadec-1-ene-4,6-diyne-3,9,10-triol.
引用
收藏
页码：737 / 738
页数：2
相关论文
共 50 条
  • [1] Asymmetric total syntheses of panaxytriol and panaxydol, potent antitumor agents from Panax ginseng
    Yadav, JS
    Maiti, A
    TETRAHEDRON, 2002, 58 (24) : 4955 - 4961
  • [2] Synthesis of the (3R, 9S, 10S)- diastereoisomer of panaxytriol, a potent antitumor polyacetylene from Panax ginseng
    Lu, W
    Zheng, GR
    Shen, JS
    Cai, JC
    CHINESE CHEMICAL LETTERS, 1999, 10 (03) : 201 - 204
  • [3] Synthesis of the (3R, 9S, 10S)-Diastereoisomer of Panaxytriol,a Potent Antitumor Polyacetylene from Panax ginseng
    Wei LU
    Guang Rong ZHENG
    Jing Shan SHEN
    Jun Chao CAI(Shanghai Institute of Materia Medica Chinese Academy of Sciences
    ChineseChemicalLetters, 1999, (03) : 3 - 5
  • [4] In Vitro Anti-Helicobacterpylori activity of Panaxytriol isolated from Ginseng
    Eun-Ah Bae
    Myung Joo Han
    Nam-In Baek
    Dong-Hyun Kim
    Archives of Pharmacal Research, 2001, 24 : 297 - 299
  • [5] In vitro anti-Helicobacter pylori activity of panaxytriol isolated from ginseng
    Bae, EA
    Han, MJ
    Baek, NI
    Kim, DH
    ARCHIVES OF PHARMACAL RESEARCH, 2001, 24 (04) : 297 - 299
  • [6] Total Synthesis of Potent Antitumor Agent (-)-Lasonolide A: A Cycloaddition-Based Strategy
    Ghosh, Arun K.
    Gong, Gangli
    CHEMISTRY-AN ASIAN JOURNAL, 2008, 3 (10) : 1811 - 1823
  • [7] Immunomodulating activities of polysaccharides isolated from Panax ginseng
    Lim, TS
    Na, K
    Choi, EM
    Chung, JY
    Hwang, JK
    JOURNAL OF MEDICINAL FOOD, 2004, 7 (01) : 1 - 6
  • [8] Practical First Total Synthesis of the Potent Phytotoxic (±)-Naphthotectone, Isolated from Tectona grandis
    Guerrero-Vasquez, Guillermo A.
    Andrade, Carlos Kleber Z.
    Molinillo, Jose M. G.
    Macias, Francisco A.
    EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2013, 2013 (27) : 6175 - 6180
  • [9] Achromobacter panacis sp nov., isolated from rhizosphere of Panax ginseng
    Singh, Priyanka
    Kim, Yeon Ju
    Singh, Hina
    Farh, Mohamed El-Agamy
    Yang, Deok-Chun
    JOURNAL OF MICROBIOLOGY, 2017, 55 (06) : 428 - 434
  • [10] First total synthesis of optically active oplopandiol acetate, a potent antimycobacterial polyyne isolated from Oplopanax horridus
    Xu, LA
    Wu, XH
    Zheng, GR
    Cai, JC
    CHINESE CHEMICAL LETTERS, 2000, 11 (03) : 213 - 216
12345