A review of hematopoietic stem cell transplantation for autoimmune diseases: multiple sclerosis, systemic sclerosis and Crohn's disease. Position paper of the Brazilian Society of Bone Marrow Transplantation

被引：15

作者：

Oliveira, Maria Carolina ^{[1
]}

Elias, Juliana Bernardes ^{[1
]}

de Moraes, Daniela Aparecida ^{[1
]}

Simoes, Belinda Pinto ^{[1
]}

Rodrigues, Morgani ^{[2
]}

Ribeiro, Andreza Alice Feitosa ^{[2
]}

Piron-Ruiz, Lilian ^{[3
]}

Ruiz, Milton Arthur ^{[3
]}

Hamerschlak, Nelson ^{[2
]}

机构：

[1] Univ Sao Paulo FMRP USP, Fac Med Ribeirao Preto, Ribeirao Preto, SP, Brazil

[2] Hosp Israelita Albert Einstein, Sao Paulo, SP, Brazil

[3] Associacao Portuguesa Beneficencia Sao Jose Do Ri, Sao Jose Do Rio Preto, SP, Brazil

来源：

HEMATOLOGY TRANSFUSION AND CELL THERAPY | 2021年 / 43卷 / 01期

关键词：

Multiple sclerosis; Crohn disease; Systemic scleroderma; Diffuse scleroderma; Bone marrow transplantation; DOSE IMMUNOSUPPRESSIVE THERAPY; TERM-FOLLOW-UP; AUTOLOGOUS PERIPHERAL-BLOOD; INFLAMMATORY-BOWEL-DISEASE; WORKING PARTY; EUROPEAN GROUP; PULSE CYCLOPHOSPHAMIDE; CONDITIONING REGIMEN; HODGKINS-LYMPHOMA; SCLERODERMA LUNG;

D O I：

10.1016/j.htct.2020.03.002

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Autoimmune diseases are an important field for the development of bone marrow transplantation, or hematopoietic stem cell transplantation. In Europe alone, almost 3000 procedures have been registered so far. The Brazilian Society for Bone Marrow Transplantation (Sociedade Brasileira de Transplantes de Medula Ossea) organized consensus meetings for the Autoimmune Diseases Group, to review the available literature on hematopoietic stem cell transplantation for autoimmune diseases, aiming to gather data that support the procedure for these patients. Three autoimmune diseases for which there are evidence-based indications for hematopoietic stem cell transplantation are multiple sclerosis, systemic sclerosis and Crohn's disease. The professional stem cell transplant societies in America, Europe and Brazil (Sociedade Brasileira de Transplantes de Medula Ossea) currently consider hematopoietic stem cell transplantation as a therapeutic modality for these three autoimmune diseases. This article reviews the evidence available. (C) 2021 Associacao Brasileira de Hematologia, Hemoterapia e Terapia Celular. Published by Elsevier Editora Ltda.

引用

页码：65 / 86

页数：22

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