IL-4 inducibility in NKT cells, naive CD4+ T cells and TCR-γ δ T cells

被引：3
|
作者：
Chen, Yi-Ting [1 ]
Kung, John T. [1 ]
机构：
[1] Acad Sinica, Inst Mol Biol, Taipei 11529, Taiwan
来源：
JOURNAL OF BIOMEDICAL SCIENCE | 2007年 / 14卷 / 04期
关键词：
IL-4; inducibility; naive CD4(+) T cells; NKT cell; post-thymic regulation; TCR-gamma delta T cell; thymus;
D O I：
10.1007/s11373-007-9167-1
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
NKT cells, naive CD4(+) T cells, and TCR-gamma delta T cells belong to distinct T cell lineages but all express T cell receptors generated through random combinatorial joining of V-(D)-J genes. These distinct lineage T cells also possess the property of promptly activating the IL-4 gene upon T cell receptor stimulation. A comparative accounting of features as they pertain to IL-4 inducibility in these three distinct lineage T cells is provided here.
引用
收藏
页码：533 / 538
页数：6
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