The impact of candidemia on length of hospital stay, outcome, and overall cost of illness

被引:249
作者
Rentz, AM
Halpern, MT
Bowden, R
机构
[1] MEDTAP Int, Bethesda, MD 20814 USA
[2] Univ Washington, Fred Hutchinson Canc Ctr, Seattle, WA 98195 USA
关键词
D O I
10.1086/514955
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Although numerous studies have examined trends in nosocomial fungal infections, few have specifically addressed the cost of care associated with candidemia. This study analyzes the direct medical costs associated with treating candidemia in the United States. The study design was a cost-of-illness analysis estimating the average cost of candidemia for a single episode of care. Data were obtained from three sources: the 1993 Healthcare Cost and Utilization Project of the Agency for Health Care Policy and Research, the relevant literature, and a clinical expert in systemic fungal infections. The estimated cost (1997 U.S, $) of an episode of care for candidemia is $34,123 per Medicare patient and $44,536 per private insurance patient. The major cost associated with candidemia is that of an increased hospital stay. The estimated cost of care for candidemia may change in the future because of the use of more expensive antifungal treatments with improved safety and efficacy profiles.
引用
收藏
页码:781 / 788
页数:8
相关论文
共 27 条
[1]   SECULAR TRENDS IN NOSOCOMIAL PRIMARY BLOOD-STREAM INFECTIONS IN THE UNITED-STATES, 1980-1989 [J].
BANERJEE, SN ;
EMORI, TG ;
CULVER, DH ;
GAYNES, RP ;
JARVIS, WR ;
HORAN, T ;
EDWARDS, JR ;
TOLSON, J ;
HENDERSON, T ;
MARTONE, WJ .
AMERICAN JOURNAL OF MEDICINE, 1991, 91 :S86-S89
[2]  
COMO JA, 1994, NEW ENGL J MED, V330, P263, DOI 10.1056/NEJM199401273300407
[3]   CANDIDEMIA IN CHILDREN WITH CENTRAL VENOUS CATHETERS - ROLE OF CATHETER REMOVAL AND AMPHOTERICIN-B THERAPY [J].
DATO, VM ;
DAJANI, AS .
PEDIATRIC INFECTIOUS DISEASE JOURNAL, 1990, 9 (05) :309-314
[4]   CANDIDEMIA - CURRENT EPIDEMIOLOGIC CHARACTERISTICS AND A LONG-TERM FOLLOW-UP OF THE SURVIVORS [J].
DEBUSK, CH ;
DAOUD, R ;
THIRUMOORTHI, MC ;
WILSON, FM ;
KHATIB, R .
SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES, 1994, 26 (06) :697-703
[5]  
*DEP HLTH HUM SERV, 1994, HEALTHC COST UT PROJ
[6]  
DONAHUE SP, 1994, OPHTHALMOLOGY, V101, P1302, DOI 10.1016/S0161-6420(94)31175-4
[7]  
DONOWITZ LG, 1995, PEDIATRICS, V95, P888
[8]   SHOULD ALL PATIENTS WITH CANDIDEMIA BE TREATED WITH ANTIFUNGAL AGENTS [J].
EDWARDS, JE .
CLINICAL INFECTIOUS DISEASES, 1992, 15 (03) :422-423
[9]   International Conference for the Development of a Consensus on the Management and Prevention of Severe Candidal Infections [J].
Edwards, JE ;
Bodey, GP ;
Bowden, RA ;
Buchner, T ;
dePauw, BE ;
Filler, SG ;
Ghannoum, MA ;
Glauser, M ;
Herbrecht, R ;
Kauffman, CA ;
Kohno, S ;
Martino, P ;
Meunier, F ;
Mori, T ;
Pfaller, MA ;
Rex, JH ;
Rogers, TR ;
Rubin, RH ;
Solomkin, J ;
Viscoli, C ;
Walsh, TJ ;
White, M .
CLINICAL INFECTIOUS DISEASES, 1997, 25 (01) :43-59
[10]   CANDIDEMIA IN A TERTIARY CARE HOSPITAL - EPIDEMIOLOGY, RISK-FACTORS, AND PREDICTORS OF MORTALITY [J].
FRASER, VJ ;
JONES, M ;
DUNKEL, J ;
STORFER, S ;
MEDOFF, G ;
DUNAGAN, WC .
CLINICAL INFECTIOUS DISEASES, 1992, 15 (03) :414-421