Fungal Morphogenesis

被引:46
作者
Lin, Xiaorong [1 ]
Alspaugh, J. Andrew [2 ]
Liu, Haoping [3 ]
Harris, Steven [4 ]
机构
[1] Texas A&M Univ, Dept Biol, College Stn, TX 77843 USA
[2] Duke Univ, Med Ctr, Dept Med, Div Infect Dis, Durham, NC 27710 USA
[3] Univ Calif Irvine, Dept Biol Chem, Irvine, CA 92697 USA
[4] Univ Nebraska, Ctr Plant Sci Innovat, Lincoln, NE 68588 USA
来源
COLD SPRING HARBOR PERSPECTIVES IN MEDICINE | 2015年 / 5卷 / 02期
基金
美国国家科学基金会;
关键词
PROTEIN-COUPLED RECEPTOR; CELL-WALL BIOGENESIS; CANDIDA-ALBICANS; CRYPTOCOCCUS-NEOFORMANS; ASPERGILLUS-NIDULANS; HYPHAL GROWTH; BLASTOMYCES-DERMATITIDIS; BIOFILM FORMATION; SACCHAROMYCES-CEREVISIAE; HISTOPLASMA-CAPSULATUM;
D O I
10.1101/cshperspect.a019679
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Morphogenesis in fungi is often induced by extracellular factors and executed by fungal genetic factors. Cell surface changes and alterations of the microenvironment often accompany morphogenetic changes in fungi. In this review, we will first discuss the general traits of yeast and hyphal morphotypes and how morphogenesis affects development and adaptation by fungi to their native niches, including host niches. Then we will focus on the molecular machinery responsible for the two most fundamental growth forms, yeast and hyphae. Last, we will describe how fungi incorporate exogenous environmental and host signals together with genetic factors to determine their morphotype and how morphogenesis, in turn, shapes the fungal microenvironment.
引用
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页数:25
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