Synthesis, structure and thermal stability of fully hydrophobic porphyrin-DNA conjugates

被引：18
|
作者：
Murashima, Takashi [1 ,2 ]
Hayata, Kazuyuki [2 ]
Saiki, Yumi [2 ]
Matsui, Jun [1 ,2 ]
Miyoshi, Daisuke [1 ,2 ]
Yamada, Takashi [2 ]
Miyazawa, Toshifumi [2 ]
Sugimoto, Naoki [1 ,2 ]
机构：
[1] Konan Univ, FIBER, Higashinada Ku, Kobe, Hyogo 6588501, Japan
[2] Konan Univ, Dept Chem, Fac Sci & Engn, Higashinada Ku, Kobe, Hyogo 6588501, Japan
来源：
TETRAHEDRON LETTERS | 2007年 / 48卷 / 48期
关键词：
D O I：
10.1016/j.tetlet.2007.09.147
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The DNAs modified with tetraphenyl porphyrin at the center of 13mer oligonucleotide were synthesized using phosphoramidite chemistry and automated DNA synthesis. When the porphyrin modified oligonucleotide was annealed with its complementary strand, they formed a standard B-form duplex. The porphyrin moiety intercalated in the duplex, and moderately lowered the thermal stability. (C) 2007 Elsevier Ltd. All rights reserved.
引用
收藏
页码：8514 / 8517
页数：4
相关论文
共 50 条
  • [31] On synthesis, structure, and thermal stability of mercury and lead sulfates and oxide sulfates
    Ahmed, MAK
    Fjellvåg, H
    Kjekshus, A
    THERMOCHIMICA ACTA, 2002, 390 (1-2) : 113 - 121
  • [32] SYNTHESIS, CRYSTALLINE-STRUCTURE AND THERMAL-STABILITY OF HAFNIUM MONOCHLORIDE
    IZMAILOV.AS
    TROYANOV, SI
    TSIRELNI.VI
    ZHURNAL NEORGANICHESKOI KHIMII, 1974, 19 (11): : 2922 - 2924
  • [33] Significantly Enhanced DNA Thermal Stability Resulting from Porphyrin H-Aggregate Formation in the Minor Groove of the Duplex
    Stephenson, Adam W. I.
    Bomholt, Niels
    Partridge, Ashton C.
    Filichev, Vyacheslav V.
    CHEMBIOCHEM, 2010, 11 (13) : 1833 - 1839
  • [34] Thermal stability improved by π-π stacking interactions: Synthesis, crystal structure and thermal decomposition of sodium nitroformate
    Huisheng Huang
    Jin Zhang
    Tonglai Zhang
    Shengtao Zhang
    Journal of Wuhan University of Technology-Mater. Sci. Ed., 2014, 29 : 488 - 491
  • [35] Thermal Stability Improved by π–π Stacking Interactions: Synthesis, Crystal Structure and Thermal Decomposition of Sodium Nitroformate
    黄辉胜
    ZHANG Jin
    张同来
    张胜涛
    Journal of Wuhan University of Technology(Materials Science Edition), 2014, 29 (03) : 488 - 491
  • [36] Thermal Stability Improved by π-π Stacking Interactions: Synthesis, Crystal Structure and Thermal Decomposition of Sodium Nitroformate
    Huang Huisheng
    Zhang Jin
    Zhang Tonglai
    Zhang Shengtao
    JOURNAL OF WUHAN UNIVERSITY OF TECHNOLOGY-MATERIALS SCIENCE EDITION, 2014, 29 (03): : 488 - 491
  • [37] Oligonucleotide-minor groove binder conjugates and their complexes with complementary DNA:: Effect of conjugate structural factors on the thermal stability of duplexes
    Ryabinin, VA
    Boutorine, AS
    Hélène, C
    Pyshnyi, DV
    Sinyakov, AN
    NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS, 2004, 23 (05): : 789 - 803
  • [38] Synthesis, Crystal Structure and Thermal Stability of (Diacetylacetone)(diimidazole)Nickel(II) Complex
    JIAN Fang-Fang② PANG Lei XIAO Hai-Lian SUN Ping-Ping (New Materials & Function Coordination Chemistry Laboratory
    结构化学, 2004, (09) : 975 - 978
  • [39] Synthesis, Crystal Structure, Thermal Stability, and Herbicidal Activity of Dinuclear Trialkyltin Aryloxyacetates
    Tan, Y. X.
    Yu, J. X.
    Feng, Y. L.
    Kuang, D. Z.
    RUSSIAN JOURNAL OF GENERAL CHEMISTRY, 2023, 93 (02) : 398 - 402
  • [40] Synthesis, structure, mechanical properties, and thermal stability of some polysulfone/organoclay nanocomposites
    Sur, GS
    Sun, HL
    Lyu, SG
    Mark, JE
    POLYMER, 2001, 42 (24) : 9783 - 9789
12345