ResistoMap-online visualization of human gut microbiota antibiotic resistome

被引：20

作者：

Yarygin, Konstantin S. ^{[1
,2
]}

Kovarsky, Boris A. ^{[2
]}

Bibikova, Tatyana S. ^{[3
]}

Melnikov, Damir S. ^{[3
]}

Tyakht, Alexander V. ^{[1
,2
]}

Alexeev, Dmitry G. ^{[1
,2
]}

机构：

[1] MIPT, 9 Inst Per, Dolgoprudnyi 141700, Moscow Region, Russia

[2] FRCC PCM, Malaya Pirogovskaya 1a, Moscow 119435, Russia

[3] Data Lab, Kostycheva 64-12, Bryansk 241037, Russia

来源：

BIOINFORMATICS | 2017年 / 33卷 / 14期

基金：

俄罗斯科学基金会;

关键词：

METAGENOME; DATABASE;

D O I：

10.1093/bioinformatics/btx134

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

We created ResistoMap-a Web-based interactive visualization of the presence of genetic determinants conferring resistance to antibiotics, biocides and heavy metals in human gut microbiota. ResistoMap displays the data on more than 1500 published gut metagenomes of world populations including both healthy subjects and patients. Multiparameter display filters allow visual assessment of the associations between the meta-data and proportions of resistome. The geographic map navigation layer allows to state hypotheses regarding the global trends of antibiotic resistance and correlates the gut resistome variations with the national clinical guidelines on antibiotics application.

引用

页码：2205 / 2206

页数：2

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