Catheter-related Candidemia Caused by Candida haemulonii in a Patient in Long-term Hospital Care

被引:36
作者
Kim, Sunyong [1 ]
Ko, Kwan Soo [2 ,3 ]
Moon, Su Yeon [1 ]
Lee, Mi Suk [1 ]
Lee, Mi Young [2 ]
Son, Jun Seong [1 ]
机构
[1] Kyung Hee Univ, Coll Med, Dept Internal Med, Div Infect Dis, Seoul 130702, South Korea
[2] APFID, Seoul, South Korea
[3] Sungkyunkwan Univ, Dept Mol Cell Biol, Sch Med, Suwon, South Korea
关键词
Cardida haemulonii; Candidemia; Caspofungin; Echinocandins; ANTIFUNGAL SUSCEPTIBILITY; AMPHOTERICIN-B; FLUCONAZOLE; RESISTANT; FUNGEMIA; KOREA; YEAST;
D O I
10.3346/jkms.2011.26.2.297
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Candida haemulonii, one of the non-albicans Candida species, is an emerging yeast pathogen that is known to be resistant to amphotericin B and other antifungal agents such as azoles. These anti-fungal agents have often been associated with clinical treatment failure, so no treatment regimen has been clearly established for invasive C. haemulonii infections. We investigated a catheter-related infection of C. haemulonii candidemia in an adult patient in long-term hospital care. In the early stages, the candidemia remained persistent despite treatment with fluconazole. However, after changing the antifungal agent to caspofungin, the candidemia was resolved. Fluconazole and amphotericin B are not reliable empirical antifungal agents for invasive C. haemulonii infections, as shown in previous case reports. An echinocandin such as caspofungin may be an appropriate empirical choice of antifungal agent for an invasive C. haemulonii infection.
引用
收藏
页码:297 / 300
页数:4
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