In vitro activity of four fluoroquinolones against Mycobacterium tuberculosis

被引：69

作者：

Rodríguez, JC ^{[1
]}

Ruiz, M ^{[1
]}

Climent, A ^{[1
]}

Royo, G ^{[1
]}

机构：

[1] Univ Miguel Hernandez, Hosp Gen Univ Elche, Microbiol Sect, Alicante 03202, Spain

来源：

INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS | 2001年 / 17卷 / 03期

关键词：

Mycobacterium tuberculosis; fluoroquinolones; moxifloxacin;

D O I：

10.1016/S0924-8579(00)00337-X

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

The in vitro activity of ciprofloxacin, ofloxacin. levofloxacin and moxifloxacin against strains of Mycobacterium tuberculosis was studied. Moxifloxacin and levofloxacin showed the greatest activity having an MIC90 of 1 mg/l. The MIC90 for ofloxacin was 2 mg/l and for ciprofloxacin 4 mg/l. Further studies should be made to determine the role played by these compounds in the treatment of tuberculosis. (C) 2001 Elsevier Science B.V. and International Society of Chemotherapy All rights reserved.

引用

页码：229 / 231

页数：3

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