Effects of Exercise Intervention on Health-Related Quality of Life in Patients with Systemic Lupus Erythematosus: A Systematic Review and Meta-Analysis of Controlled Trials

被引：14
作者：
Lu, Ming-Chi [1 ,2 ]
Koo, Malcolm [3 ,4 ]
机构：
[1] Buddhist Tzu Chi Med Fdn, Dalin Tzu Chi Hosp, Div Allergy Immunol & Rheumatol, Chiayi 62247, Taiwan
[2] Tzu Chi Univ, Sch Med, Hualien 97004, Taiwan
[3] Tzu Chi Univ Sci & Technol, Grad Inst Long Term Care, Hualien 970302, Taiwan
[4] Univ Toronto, Dalla Lana Sch Publ Hlth, Toronto, ON M5T 3M7, Canada
来源：
HEALTHCARE | 2021年 / 9卷 / 09期
关键词：
exercise; physical activity; quality of life; systemic lupus erythematosus; systematic review; meta-analysis; PHYSICAL-ACTIVITY PROGRAM; AEROBIC CAPACITY; PREVALENCE; VALIDATION; FATIGUE; ADULTS; WOMEN;
D O I：
10.3390/healthcare9091215
中图分类号：
R19 [保健组织与事业（卫生事业管理）];
学科分类号：
摘要：
Exercise and physical activity have been deemed as potentially beneficial for patients with systemic lupus erythematosus (SLE). This study aimed to evaluate the effects of exercise interventions on health-related quality of life in patients with SLE using a systematic review and meta-analysis. Randomized and non-randomized controlled trials published up to July 2021 were examined using the PubMed and Embase databases. Of the 1158 articles retrieved, nine were included for systematic review. Five of them were randomized controlled trials and these were assessed using meta-analysis. Hedges' g effect size was 0.47; 95% (confidence interval 0.21-0.73; p < 0.001) for the physical health and function aspect of health-related quality of life. None of the other seven domains of the SF-36 showed a significant effect size. However, the latter finding was limited by the small number of available trials. In conclusion, this systematic review and meta-analysis supported that exercise intervention compared to usual care might be able to improve the physical functioning domain of health-related quality of life in patients with SLE. Future high-quality randomized controlled trials that incorporate disease-specific health-related quality of life measures are needed to elucidate the role of exercise on health-related quality of life in patients with SLE.
引用
收藏
页数：15
相关论文
共 42 条
[31]   Reduced Aerobic Capacity and Quality of Life in Physically Inactive Patients With Systemic Lupus Erythematosus With Mild or Inactive Disease [J].
Pinto, Ana J. ;
Miyake, Cintia N. H. ;
Benatti, Fabiana B. ;
Silva, Clovis A. ;
Sallum, Adriana M. E. ;
Borba, Eduardo ;
de Sa-Pinto, Ana L. ;
Bonfa, Eloisa ;
Gualano, Bruno .
ARTHRITIS CARE & RESEARCH, 2016, 68 (12) :1780-1786
[32]   Understanding the Epidemiology and Progression of Systemic Lupus Erythematosus [J].
Pons-Estel, Guillermo J. ;
Alarcon, Graciela S. ;
Scofield, Lacie ;
Reinlib, Leslie ;
Cooper, Glinda S. .
SEMINARS IN ARTHRITIS AND RHEUMATISM, 2010, 39 (04) :257-268
[33]  
Ramsey-Goldman R, 2000, ARTHRIT CARE RES, V13, P262, DOI 10.1002/1529-0131(200010)13:5<262::AID-ANR4>3.0.CO
[34]  
2-8
[35]  
SCHIPPER H, 1990, Journal of Psychosocial Oncology, V8, P171, DOI 10.1300/J077v08n02_09
[36]   Relationship between disease activity, organ damage and health-related quality of life in patients with systemic lupus erythematosus: A systemic review and meta-analysis [J].
Shi, Yue ;
Li, Mucong ;
Liu, Lingshan ;
Wang, Ziqian ;
Wang, Yanhong ;
Zhao, Jiuliang ;
Wang, Qian ;
Tian, Xinping ;
Li, Mengtao ;
Zeng, Xiaofeng .
AUTOIMMUNITY REVIEWS, 2021, 20 (01)
[37]   Effects of resistance training on the health-related quality of life of patients with rheumatic diseases: Systematic review with meta-analysis and meta-regression [J].
Sieczkowska, Sofia Mendes ;
Coimbra, Danilo Reis ;
Vilarino, Guilherme Torres ;
Andrade, Alexandro .
SEMINARS IN ARTHRITIS AND RHEUMATISM, 2020, 50 (02) :342-353
[38]   RoB 2: a revised tool for assessing risk of bias in randomised trials [J].
Sterne, Jonathan A. C. ;
Savovic, Jelena ;
Page, Matthew J. ;
Elbers, Roy G. ;
Blencowe, Natalie S. ;
Boutron, Isabelle ;
Cates, Christopher J. ;
Cheng, Hung-Yuan ;
Corbett, Mark S. ;
Eldridge, Sandra M. ;
Emberson, Jonathan R. ;
Hernan, Miguel A. ;
Hopewell, Sally ;
Hrobjartsson, Asbjorn ;
Junqueira, Daniela R. ;
Juni, Peter ;
Kirkham, Jamie J. ;
Lasserson, Toby ;
Li, Tianjing ;
McAleenan, Alexandra ;
Reeves, Barnaby C. ;
Shepperd, Sasha ;
Shrier, Ian ;
Stewart, Lesley A. ;
Tilling, Kate ;
White, Ian R. ;
Whiting, Penny F. ;
Higgins, Julian P. T. .
BMJ-BRITISH MEDICAL JOURNAL, 2019, 366
[39]   Fatigue in systemic lupus erythematosus: a randomized controlled trial of exercise [J].
Tench, CM ;
McCarthy, J ;
McCurdie, I ;
White, PD ;
D'Cruz, DP .
RHEUMATOLOGY, 2003, 42 (09) :1050-1054
[40]   The Effectiveness of Exercise in Adults With Systemic Lupus Erythematosus: A Systematic Review and Meta-Analysis to Guide Evidence-Based Practice [J].
Wu, Mei-Ling ;
Yu, Kuang-Hui ;
Tsai, Jen-Chen .
WORLDVIEWS ON EVIDENCE-BASED NURSING, 2017, 14 (04) :306-315
12345