Whole-body diffusion-weighted imaging for staging malignant lymphoma in children

被引:61
|
作者
Kwee, Thomas C. [1 ]
Takahara, Taro [1 ]
Vermoolen, Malou A. [1 ]
Bierings, Marc B. [2 ]
Mali, Willem P. [1 ]
Nievelstein, Rutger A. J. [1 ]
机构
[1] Univ Med Ctr Utrecht, Dept Radiol, NL-3584 CX Utrecht, Netherlands
[2] Univ Med Ctr Utrecht, Dept Pediat Hematol, NL-3584 CX Utrecht, Netherlands
关键词
Whole-body MRI; Diffusion-weighted imaging; Malignant lymphoma; Children; MRI; POSITRON-EMISSION-TOMOGRAPHY; SUPERPARAMAGNETIC IRON-OXIDE; BONE-MARROW INVOLVEMENT; NON-HODGKINS-LYMPHOMAS; COMPUTED-TOMOGRAPHY; F-18-FDG PET; POSTTREATMENT EVALUATION; SIGNAL SUPPRESSION; FAT-SUPPRESSION; BENIGN;
D O I
10.1007/s00247-010-1775-7
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
CT is currently the mainstay in staging malignant lymphoma in children, but the risk of second neoplasms due to ionizing radiation associated with CT is not negligible. Whole-body MRI techniques and whole-body diffusion-weighted imaging (DWI) in particular, may be a good radiation-free alternative to CT. DWI is characterized by high sensitivity for the detection of lesions and allows quantitative assessment of diffusion that may aid in the evaluation of malignant lymphomas. This article will review whole-body MRI techniques for staging malignant lymphoma with emphasis on whole-body DWI. Furthermore, future considerations and challenges in whole-body DWI will be discussed.
引用
收藏
页码:1592 / 1602
页数:11
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