Assessment of Neutrophil-to-Lymphocyte Ratio and Platelet-to-Lymphocyte Ratio in Patients with Dry Eye Disease

被引：39

作者：

Celik, Tuba ^{[1
]}

机构：

[1] Bulent Ecevit Univ, Dept Ophthalmol, Fac Med, Zonguldak, Turkey

来源：

OCULAR IMMUNOLOGY AND INFLAMMATION | 2018年 / 26卷 / 08期

关键词：

Dry eye disease biomarkers; inflammation; neutrophil-to-lymphocyte ratio; platelet-to-lymphocyte ratio; NEUTROPHIL/LYMPHOCYTE RATIO; INFLAMMATORY MARKERS; CLASSIFICATION; ASSOCIATION;

D O I：

10.1080/09273948.2017.1340486

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

Purpose: To evaluate the neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) levels in patients with dry eye disease (DED). Methods: The white blood cell, neutrophil, platelet, and lymphocyte counts were performed in 78 dry eye patients and 60 controls. The NLR was calculated by dividing neutrophil count by lymphocyte count and the PLR was calculated by dividing platelet count by lymphocyte count. Results: The mean age was 53.4 +/- 3.8 years in the DED group and 52.7 +/- 3.4 years in the control group. The mean NLR was 2.6 +/- 1.2 and the mean PLR was 138.4 +/- 62.6 in the DED group and the mean NLR was 1.84 +/- 0.5 and the mean PLR was 118.5 +/- 64.7 in the control group. A significant difference was found in the NLR and PLR between the DED and the controls (p = 0.032 and p = 0.026, respectively). Conclusion: The NLR and PLR values were found higher in patients with dry eye than in healthy subjects.

引用

页码：1219 / 1222

页数：4

共 23 条

[1] The Relation Between Neutrophil-Lymphocyte Ratio and Hypertension [J].

Balta, Sevket ;

Ozturk, Cengiz ;

Yildirim, Ali Osman ;

Aparci, Mustafa ;

Demir, Mustafa ;

Celik, Turgay .

AMERICAN JOURNAL OF HYPERTENSION, 2015, 28 (11) :1386-1386

[2]

Brignole F, 2001, INVEST OPHTH VIS SCI, V42, P90

[3] Prognostic Value of Pre-Operative Platelet to Lymphocyte Ratio in Patients with Resected Primary Hepatocellular Carcinoma [J].

Dong, Lihong ;

Bai, Kai ;

Cao, Yi ;

Huang, Qiaojia ;

Lv, Lizhi ;

Jiang, Yi .

CLINICAL LABORATORY, 2016, 62 (11) :2191-2196

[4] Association of neutrophil/lymphocyte ratio and retinal vein occlusion [J].

Dursun, Ayhan ;

Ozturk, Sultan ;

Yucel, Hasan ;

Ozec, Ayse Vural ;

Dursun, Feyza Gulac ;

Toker, Mustafa Ilker ;

Erdogan, Haydar ;

Arici, Mustafa Kemal ;

Topalkara, Aysen .

EUROPEAN JOURNAL OF OPHTHALMOLOGY, 2015, 25 (04) :343-346

[5] Elevated Neutrophil Lymphocyte Ratio in Recurrent Optic Neuritis [J].

Guclu, Hande ;

Ozal, Sadik Altan ;

Gurlu, Vuslat Pelitli ;

Birgul, Ramazan .

JOURNAL OF OPHTHALMOLOGY, 2015, 2015

[6] The Significance of the Neutrophil/Lymphocyte Ratio as a Simple Indicator of Inflammation in Age-related Macular Degeneration REPLY [J].

Ilhan, Nilufer ;

Daglioglu, Mutlu Cihan ;

Ilhan, Ozgur ;

Coskun, Mesut ;

Tuzcu, Esra Ayhan ;

Kahraman, Hilal ;

Keskin, Ugurcan .

OCULAR IMMUNOLOGY AND INFLAMMATION, 2016, 24 (03) :362-363

[7] Neutrophil-to-Lymphocyte Ratio May Predict Progression in Patients With Keratoconus [J].

Karaca, Emine Esra ;

Ozmen, Mehmet Cuneyt ;

Ekici, Feyzahan ;

Yuksel, Erdem ;

Turkoglu, Zulal .

CORNEA, 2014, 33 (11) :1168-1173

[8]

Lemp MA, 2007, OCUL SURF, V5, P75

[9] Platelet to lymphocyte ratio in the prediction of adverse outcomes after acute coronary syndrome: a meta-analysis [J].

Li, Wenzhang ;

Liu, Qianqian ;

Tang, Yin .

SCIENTIFIC REPORTS, 2017, 7

[10] Relationship between neutrophil-lymphocyte ratio and insulin resistance in newly diagnosed type 2 diabetes mellitus patients [J].

Lou, Meiqin ;

Luo, Peng ;

Tang, Ru ;

Peng, Yixian ;

Yu, Siyuan ;

Huang, Wanjing ;

He, Lei .

BMC ENDOCRINE DISORDERS, 2015, 15

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