ATM: the p53 booster

被引：33
|
作者：
Nakamura, Y [1 ]
机构：
[1] Univ Tokyo, Inst Med Sci, Ctr Human Genome, Mol Med Lab, Tokyo, Japan
来源：
NATURE MEDICINE | 1998年 / 4卷 / 11期
关键词：
D O I：
10.1038/3207
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The ATM gene (mutated in the disease ataxia telangiectasia) activates the p53 tumor suppressor protein in response to DNA damage, explaining the higher incidence of cancer in AT patients.
引用
收藏
页码：1231 / 1232
页数：2
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