Insomnia, Health-Related Quality of Life and Health Outcomes in Children: A Seven Year Longitudinal Cohort

被引:51
作者
Combs, Daniel [1 ,2 ,3 ]
Goodwin, James L. [3 ]
Quan, Stuart F. [3 ,4 ,5 ]
Morgan, Wayne J. [1 ,3 ]
Shetty, Safal [2 ,3 ,6 ,7 ]
Parthasarathy, Sairam [2 ,3 ,6 ,7 ]
机构
[1] Univ Arizona, Dept Pediat, Tucson, AZ 85721 USA
[2] Univ Arizona, Dept Med, Tucson, AZ USA
[3] Univ Arizona, Arizona Resp Ctr, Tucson, AZ USA
[4] Harvard Univ, Div Sleep & Circadian Disorders, Brigham & Womens Hosp, Sch Med, Boston, MA USA
[5] Harvard Univ, Div Sleep Med, Sch Med, Boston, MA USA
[6] Univ Arizona, Ctr Sleep Disorders, Tucson, AZ USA
[7] Univ Arizona, Div Pulm Allergy Crit Care & Sleep Med, Tucson, AZ USA
基金
美国国家卫生研究院;
关键词
SLEEP PROBLEMS; SELF-HARM; ADOLESCENTS; SYMPTOMS; PREVALENCE; PERSISTENCE; DISTURBANCES; ASSOCIATIONS; CHILDHOOD; MORTALITY;
D O I
10.1038/srep27921
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Insomnia is common in children, and is associated with decreased school performance and increased psychopathology. Although adult insomnia is linked to worsened health-related quality of life (HRQOL), there is insufficient data evaluating insomnia and HRQOL in children. We examined the HRQOL and health associations of insomnia in a longitudinal cohort of 194 children (96 girls, age at study start 8.7 +/- 1.6 years, age at data analysis 15.0 +/- 1.8 years) over 7 years. International Classification of Sleep Disorders, second edition (ICSD2) derived insomnia was seen intermittently in 27% of children, and was persistent in 4%. Children reporting ICSD2-derived insomnia had lower HRQOL. Additionally, the presence of insomnia was associated with an increased risk of reporting a new medical condition (intermittent insomnia odds ratio 5.9 [95% CI 1.3-26.7, p = 0.04], persistent insomnia odds ratio 8 [95% CI 2.3-27.7, p = 0.001]). Persistent ICSD2-derived insomnia was associated with an increased risk of reporting a new medication (odds ratio 4.9 (95% CI 1.0-23.6), p = 0.049), and reporting a new psychiatric medication (odds ratio 13.7, 95% CI: 2.6-73.5, p = 0.002). These associations were present even after adjusting for socioeconomic factors and the presence of obstructive sleep apnea. Insomnia in children is associated with worsened HRQOL and health outcomes.
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页数:10
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