Study of Icaritin Films by Low-Energy Electron Beam Deposition

被引:1
作者
Cheng, Tongfei [1 ]
Cao, Jinxing [1 ]
Jiang, Xiaohong [1 ]
Yarmolenko, M. A. [2 ]
Rogachev, A. A. [2 ]
Rogachev, A. V. [2 ]
机构
[1] Nanjing Univ Sci & Technol, Int Chinese Belorussian Sci Lab Vacuum Plasma Tec, 200 Xiaolingwei Str, Nanjing 210094, Peoples R China
[2] Francisk Skorina Gomel State Univ, 104 Sovetskaya Str, Gomel 246019, BELARUS
关键词
Low-energy Electron Beam Deposition; Icaritin Film; Material Characterization; Film Release; Biocompatibility; MESENCHYMAL STEM-CELLS; BONE-MARROW; OSTEOGENIC DIFFERENTIATION; OSTEONECROSIS; SURFACES; TITANIUM;
D O I
10.18321/ectj1077
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
In this paper, icaritin film was prepared by low-energy beam electron beam deposition (EBD). The material test showed that the structure and composition of icaritin were not changed after electron beam deposition. Then, the film was sliced and immersed in simulated body fluids, it can be seen that the film was released quickly in the first 7 days. With the extension of soaking time, the release rate gradually slowed down, and the release amount exceeded 90% in about 20 days. In vitro cytotoxicity test showed that the relative cell viability rate of the film was still 92.32 +/- 1.30% (p<0.05), indicating that the film possessed excellent cytocompatibility.
引用
收藏
页码:77 / 87
页数:11
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    Choudhary, Dharmendra
    Ahmad, Naseer
    Karvande, Anirudha
    Kumar, Avinash
    Banala, Venkatesh Teja
    Mishra, Prabhat Ranjan
    Trivedi, Ritu
    [J]. NUTRITION, 2018, 53 : 64 - 76
  • [2] On the Corrosion Behaviour of Low Modulus Titanium Alloys for Medical Implant Applications: A Review
    Afzali, Pooria
    Ghomashchi, Reza
    Oskouei, Reza H.
    [J]. METALS, 2019, 9 (08)
  • [3] Increased adipogenesis of osteoporotic human-mesenchymal stem cells (MSCs) is characterized by impaired leptin action
    Astudillo, Pablo
    Rios, Susana
    Pastenes, Luis
    Pino, Ana Maria
    Rodriguez, J. Pablo
    [J]. JOURNAL OF CELLULAR BIOCHEMISTRY, 2008, 103 (04) : 1054 - 1065
  • [4] Growth factors produced by bone marrow stromal cells on nanoroughened titanium-aluminum-vanadium surfaces program distal MSCs into osteoblasts via BMP2 signaling
    Berger, Michael B.
    Bosh, Kyla B.
    Jacobs, Thomas W.
    Cohen, D. Joshua
    Schwartz, Zvi
    Boyan, Barbara D.
    [J]. JOURNAL OF ORTHOPAEDIC RESEARCH, 2021, 39 (09) : 1908 - 1920
  • [5] Fabrication of Scaffolds for Bone-Tissue Regeneration
    Chocholata, Petra
    Kulda, Vlastimil
    Babuska, Vaclav
    [J]. MATERIALS, 2019, 12 (04)
  • [6] Characterization of antimicrobial polylactic acid based films
    Erdohan, Zekiye Ozge
    Cam, Belgizar
    Turhan, Kamile Nazan
    [J]. JOURNAL OF FOOD ENGINEERING, 2013, 119 (02) : 308 - 315
  • [7] Titanium: a review on exposure, release, penetration, allergy, epidemiology, and clinical reactivity
    Fage, Simon W.
    Muris, Joris
    Jakobsen, Stig S.
    Thyssen, Jacob P.
    [J]. CONTACT DERMATITIS, 2016, 74 (06) : 323 - 345
  • [8] Adhesion of bone marrow mesenchymal stem cells on porous titanium surfaces with strontium-doped hydroxyapatite coating
    Fu, Dan-li
    Jiang, Qiao-hong
    He, Fu-ming
    Fu, Bai-ping
    [J]. JOURNAL OF ZHEJIANG UNIVERSITY-SCIENCE B, 2017, 18 (09): : 778 - 788
  • [9] A review on the wettability of dental implant surfaces II: Biological and clinical aspects
    Gittens, Rolando A.
    Scheideler, Lutz
    Rupp, Frank
    Hyzy, Sharon L.
    Geis-Gerstorfer, Juergen
    Schwartz, Zvi
    Boyan, Barbara D.
    [J]. ACTA BIOMATERIALIA, 2014, 10 (07) : 2907 - 2918
  • [10] The roles of titanium surface micro/nanotopography and wettability on the differential response of human osteoblast lineage cells
    Gittens, Rolando A.
    Olivares-Navarrete, Rene
    Cheng, Alice
    Anderson, David M.
    McLachlan, Taylor
    Stephan, Ingrid
    Geis-Gerstorfer, Juergen
    Sandhage, Kenneth H.
    Fedorov, Andrei G.
    Rupp, Frank
    Boyan, Barbara D.
    Tannenbaum, Rina
    Schwartz, Zvi
    [J]. ACTA BIOMATERIALIA, 2013, 9 (04) : 6268 - 6277