CD20: A review

被引：0
|
作者：
Chang, KL
Arber, DA
Weiss, LM
机构：
来源：
APPLIED IMMUNOHISTOCHEMISTRY | 1996年 / 4卷 / 01期
关键词：
CD20; immunohistochemistry; mature B-cells; B-cell lymphoma; B-cell ontogeny; REED-STERNBERG CELLS; HUMAN LYMPHOCYTE-B; PARAFFIN SECTION IMMUNOHISTOCHEMISTRY; NON-HODGKINS LYMPHOMA; ACUTE LYMPHOBLASTIC-LEUKEMIA; MONOCLONAL-ANTIBODIES; BONE-MARROW; DIFFERENTIATION ANTIGEN; PREDOMINANCE TYPE; EPITHELIAL-CELLS;
D O I：
暂无
中图分类号：
R602 [外科病理学、解剖学]; R32 [人体形态学];
学科分类号：
100101 ;
摘要：
CD20 is a membrane-embedded 35-37 kDa nonglycosylated phosphoprotein that is a restricted B-cell antigen. CD20 antibodies are available for paraffin and frozen section immunohistochemistry and for flow cytometric analysis. Its clinical utility is greatest for identifying B-lineage non-Hodgkin's lymphomas, but it can also aid in the diagnosis of nodular lymphocyte predominance Hodgkin's disease and acute lymphoblastic neoplasms. CD20 immunotoxins have also been used experimentally to treat B-cell lymphomas that do not respond to conventional chemotherapy or radiation therapy.
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页码：1 / 15
页数：15
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