Attention function and dysfunction in autism

被引:167
作者
Allen, G
Courchesne, E
机构
[1] Childrens Hosp Res Ctr, La Jolla, CA 92037 USA
[2] Univ Calif San Diego, Sch Med, Dept Neurosci, La Jolla, CA 92093 USA
[3] Univ Calif San Diego, Sch Med, Dept Psychiat, La Jolla, CA 92093 USA
[4] San Diego State Univ, Dept Psychol, San Diego, CA 92182 USA
来源
FRONTIERS IN BIOSCIENCE-LANDMARK | 2001年 / 6卷
关键词
autism; selective attention; sustained attention; spatial attention; shifting attention; parietal lobe; cerebellum; review;
D O I
10.2741/allen
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Impairments of attention are among the most consistently reported cognitive deficits in autism, and they continue to be a key focus of research. This is in no doubt due to the importance of normal attention function to the development of many so-called "higher level" cognitive operations, and to the likely involvement of attention dysfunction in certain clinical features of autism. Autistic individuals display a wide range of attentional abilities and deficits across the many domains of attention function, including selective, sustained, spatial, and shifting attention operations. This unique pattern of attention function and dysfunction has profound implications for the development and treatment of autistic children. The present review will explore this pattern of attentional strengths and weaknesses and the neural defects that underlie them.
引用
收藏
页码:D105 / D119
页数:15
相关论文
共 76 条
[1]   A NEW ROLE FOR THE CEREBELLUM IN COGNITIVE OPERATIONS [J].
AKSHOOMOFF, NA ;
COURCHESNE, E .
BEHAVIORAL NEUROSCIENCE, 1992, 106 (05) :731-738
[2]   Attention coordination and anticipatory control [J].
Akshoomoff, NA ;
Courchesne, E ;
Townsend, J .
CEREBELLUM AND COGNITION, 1997, 41 :575-598
[3]   Attentional activation of the cerebellum independent of motor involvement [J].
Allen, G ;
Buxton, RB ;
Wong, EC ;
Courchesne, E .
SCIENCE, 1997, 275 (5308) :1940-1943
[4]   A clinicopathological study of autism [J].
Bailey, A ;
Luthert, P ;
Dean, A ;
Harding, B ;
Janota, I ;
Montgomery, M ;
Rutter, M ;
Lantos, P .
BRAIN, 1998, 121 :889-905
[5]   HISTOANATOMIC OBSERVATIONS OF THE BRAIN IN EARLY INFANTILE-AUTISM [J].
BAUMAN, M ;
KEMPER, TL .
NEUROLOGY, 1985, 35 (06) :866-874
[6]  
Blaxton TA, 1996, J NEUROSCI, V16, P4032
[7]   ATTENTION PERFORMANCE IN AUTISM AND REGIONAL BRAIN METABOLIC-RATE ASSESSED BY POSITRON EMISSION TOMOGRAPHY [J].
BUCHSBAUM, MS ;
SIEGEL, BV ;
WU, JC ;
HAZLETT, E ;
SICOTTE, N ;
HAIER, R ;
TANGUAY, P ;
ASARNOW, R ;
CADORETTE, T ;
DONOGHUE, D ;
LAGUNASSOLAR, M ;
LOTT, I ;
PAEK, J ;
SABALESKY, D .
JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS, 1992, 22 (01) :115-125
[8]   SELECTIVE ATTENTION DEFICITS IN PERSONS WITH AUTISM - PRELIMINARY EVIDENCE OF AN INEFFICIENT ATTENTIONAL LENS [J].
BURACK, JA .
JOURNAL OF ABNORMAL PSYCHOLOGY, 1994, 103 (03) :535-543
[9]   Inverse correlation between frontal lobe and cerebellum sizes in children with autism [J].
Carper, RA ;
Courchesne, E .
BRAIN, 2000, 123 :836-844
[10]   DYSFUNCTIONAL ATTENTION IN AUTISTIC SAVANTS [J].
CASEY, BJ ;
GORDON, CT ;
MANNHEIM, GB ;
RUMSEY, JM .
JOURNAL OF CLINICAL AND EXPERIMENTAL NEUROPSYCHOLOGY, 1993, 15 (06) :933-946